HCSGD entry for GRM6


1. General information

Official gene symbolGRM6
Entrez ID2916
Gene full nameglutamate receptor, metabotropic 6
Other gene symbolsCSNB1B GPRC1F MGLUR6 mGlu6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIDAcellular_component
GO:0001640Adenylate cyclase inhibiting G-protein coupled glutamate receptor activityIEAmolecular_function
GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005789Endoplasmic reticulum membraneIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0007216G-protein coupled glutamate receptor signaling pathwayIMPbiological_process
GO:0007268Synaptic transmissionIEAbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0008066Glutamate receptor activityIMP TASmolecular_function
GO:0009584Detection of visible lightTASbiological_process
GO:0030425DendriteIEAcellular_component
GO:0035841New growing cell tipIEAcellular_component
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0050908Detection of light stimulus involved in visual perceptionIMPbiological_process
GO:0060041Retina development in camera-type eyeIEAbiological_process
GO:0090280Positive regulation of calcium ion importIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49090353710.70232596410.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2219100515
GSE13712_SHEARUp0.3474063943
GSE13712_STATICUp0.0946693853
GSE19018Up0.0768770689
GSE19899_A1Up0.1231863444
GSE19899_A2Up0.0515924507
PubMed_21979375_A1Up0.3418401412
PubMed_21979375_A2Up0.0275595225
GSE35957Up0.3019628095
GSE36640Up0.0742958462
GSE54402Down-0.1085467154
GSE9593Down-0.0784877872
GSE43922Up0.0200635636
GSE24585Up0.0375738698
GSE37065Down-0.2690220194
GSE28863_A1Down-0.0739600390
GSE28863_A2Up0.2845469145
GSE28863_A3Up0.0619044666
GSE28863_A4Down-0.0923973945
GSE48662Up0.0111137307

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.