HCSGD entry for GRM3

1. General information

Official gene symbolGRM3
Entrez ID2913
Gene full nameglutamate receptor, metabotropic 3
Other gene symbolsGLUR3 GPRC1C MGLUR3 mGlu3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001641Group II metabotropic glutamate receptor activityIEAmolecular_function
GO:0004930G-protein coupled receptor activityIEA TASmolecular_function
GO:0005246Calcium channel regulator activityIEAmolecular_function
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007194Negative regulation of adenylate cyclase activityTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008066Glutamate receptor activityTASmolecular_function
GO:0014069Postsynaptic densityIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030424AxonIEAcellular_component
GO:0042734Presynaptic membraneIEAcellular_component
GO:0043197Dendritic spineIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0050804Regulation of synaptic transmissionIEAbiological_process
GO:0097449Astrocyte projectionIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83809156190.37191798560.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0163459949
GSE13712_SHEARDown-0.0062237732
GSE13712_STATICDown-0.1381634904
GSE19018Up0.2078317758
GSE19899_A1Up0.0172092388
GSE19899_A2Down-0.1643332329
PubMed_21979375_A1Down-0.0547687177
PubMed_21979375_A2Up0.0005730013
GSE35957Down-0.1298639268
GSE36640Up0.1282275461
GSE54402Down-0.0462023094
GSE9593Up0.2313823999
GSE43922Up0.0157867716
GSE24585Down-0.4069500191
GSE37065Up0.0337580058
GSE28863_A1Down-0.2735860726
GSE28863_A2Down-0.0836610762
GSE28863_A3Up0.1310918424
GSE28863_A4Up0.0058686700
GSE48662Up0.0169788786

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

LY2140023DB05096 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018386MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.