HCSGD entry for PRSS50
1. General information
| Official gene symbol | PRSS50 |
|---|---|
| Entrez ID | 29122 |
| Gene full name | protease, serine, 50 |
| Other gene symbols | CT20 TSP50 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0004298 | Threonine-type endopeptidase activity | IMP | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0006508 | Proteolysis | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5587845599 | 0.6201830592 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1493943580 |
| GSE13712_SHEAR | Down | -0.1075619557 |
| GSE13712_STATIC | Up | 0.0392489381 |
| GSE19018 | Up | 0.3853482572 |
| GSE19899_A1 | Up | 0.0922664104 |
| GSE19899_A2 | Up | 0.2589804233 |
| PubMed_21979375_A1 | Up | 0.2233950706 |
| PubMed_21979375_A2 | Down | -0.2216070225 |
| GSE35957 | Down | -0.1391772085 |
| GSE36640 | Up | 0.1009340681 |
| GSE54402 | Up | 0.0630768935 |
| GSE9593 | Down | -0.0759058775 |
| GSE43922 | Down | -0.3368703971 |
| GSE24585 | Up | 0.1255663699 |
| GSE37065 | Down | -0.1549180251 |
| GSE28863_A1 | Down | -0.0543541886 |
| GSE28863_A2 | Up | 0.0573569451 |
| GSE28863_A3 | Up | 0.2457245194 |
| GSE28863_A4 | Up | 0.0586210085 |
| GSE48662 | Up | 0.0535567707 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022955 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
