HCSGD entry for MYLIP
1. General information
| Official gene symbol | MYLIP |
|---|---|
| Entrez ID | 29116 |
| Gene full name | myosin regulatory light chain interacting protein |
| Other gene symbols | IDOL MIR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006928 | Cellular component movement | IMP | biological_process |
| GO:0007399 | Nervous system development | IMP | biological_process |
| GO:0008092 | Cytoskeletal protein binding | IDA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010989 | Negative regulation of low-density lipoprotein particle clearance | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0019898 | Extrinsic component of membrane | IEA | cellular_component |
| GO:0031648 | Protein destabilization | IEA | biological_process |
| GO:0032803 | Regulation of low-density lipoprotein particle receptor catabolic process | IEA | biological_process |
| GO:0042632 | Cholesterol homeostasis | IEA | biological_process |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0045732 | Positive regulation of protein catabolic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0782550321 | 0.6872410737 | 0.5903556033 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1904801905 |
| GSE13712_SHEAR | Down | -1.1261171290 |
| GSE13712_STATIC | Down | -0.4562616004 |
| GSE19018 | Up | 0.1363890290 |
| GSE19899_A1 | Up | 0.1574346916 |
| GSE19899_A2 | Down | -0.1289044035 |
| PubMed_21979375_A1 | Up | 0.0929792283 |
| PubMed_21979375_A2 | Up | 0.3901348996 |
| GSE35957 | Down | -0.1937328957 |
| GSE36640 | Up | 0.3380140382 |
| GSE54402 | Up | 0.1434328257 |
| GSE9593 | Down | -0.3533470758 |
| GSE43922 | Up | 0.0511344667 |
| GSE24585 | Up | 0.5245709419 |
| GSE37065 | Up | 0.2529065260 |
| GSE28863_A1 | Up | 0.5578683163 |
| GSE28863_A2 | Up | 0.6205362867 |
| GSE28863_A3 | Down | -0.0763890598 |
| GSE28863_A4 | Up | 0.0666787802 |
| GSE48662 | Up | 0.2049279414 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-20b-5p | MIMAT0001413 | MIRT001783 | Luciferase reporter assay//Western blot;Other | Functional MTI | 17575136 |
| hsa-miR-106a-5p | MIMAT0000103 | MIRT001838 | Luciferase reporter assay//Western blot;Other | Functional MTI | 17575136 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT004066 | Luciferase reporter assay | Functional MTI | 17575136 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT004091 | Luciferase reporter assay | Functional MTI | 17575136 |
| hsa-miR-340-5p | MIMAT0004692 | MIRT019627 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028071 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045155 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
