HCSGD entry for SLC25A4
1. General information
| Official gene symbol | SLC25A4 |
|---|---|
| Entrez ID | 291 |
| Gene full name | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 |
| Other gene symbols | AAC1 ANT ANT1 PEO2 PEO3 T1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000002 | Mitochondrial genome maintenance | TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | TAS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006091 | Generation of precursor metabolites and energy | TAS | biological_process |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006863 | Purine nucleobase transport | TAS | biological_process |
| GO:0008637 | Apoptotic mitochondrial changes | IEA | biological_process |
| GO:0015207 | Adenine transmembrane transporter activity | TAS | molecular_function |
| GO:0015851 | Nucleobase transport | TAS | biological_process |
| GO:0015853 | Adenine transport | TAS | biological_process |
| GO:0015931 | Nucleobase-containing compound transport | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050796 | Regulation of insulin secretion | TAS | biological_process |
| GO:0060547 | Negative regulation of necrotic cell death | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3206091144 | 0.0906634930 | 0.9999902473 | 0.5724043656 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4420163077 |
| GSE13712_SHEAR | Down | -0.0651100034 |
| GSE13712_STATIC | Up | 0.1003954248 |
| GSE19018 | Up | 0.1272461639 |
| GSE19899_A1 | Down | -0.3692602616 |
| GSE19899_A2 | Down | -0.0438306797 |
| PubMed_21979375_A1 | Down | -0.8842737574 |
| PubMed_21979375_A2 | Down | -0.5732328405 |
| GSE35957 | Up | 0.4170648456 |
| GSE36640 | Up | 0.9032432856 |
| GSE54402 | Down | -0.2384081842 |
| GSE9593 | Up | 0.6383034444 |
| GSE43922 | Down | -0.2228815465 |
| GSE24585 | Up | 0.4821171539 |
| GSE37065 | Down | -0.0602323387 |
| GSE28863_A1 | Up | 0.0963240768 |
| GSE28863_A2 | Up | 0.0870869154 |
| GSE28863_A3 | Up | 0.0877161979 |
| GSE28863_A4 | Down | -0.2788838997 |
| GSE48662 | Down | -0.2968857882 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Adenosine triphosphate | DB00171 | NUTR00017 | EXPT00007 |
| [3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium | DB01736 | EXPT02014 |
| Carboxyatractyloside | DB02426 | EXPT01071 |
| Cardiolipin | DB03429 | EXPT00874 |
| Di-Stearoyl-3-Sn-Phosphatidylcholine | DB04178 | EXPT02512 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040699 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043491 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051905 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
