HCSGD entry for GRIN2D
1. General information
| Official gene symbol | GRIN2D |
|---|---|
| Entrez ID | 2906 |
| Gene full name | glutamate receptor, ionotropic, N-methyl D-aspartate 2D |
| Other gene symbols | EB11 GluN2D NMDAR2D NR2D |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001964 | Startle response | IEA | biological_process |
| GO:0004972 | N-methyl-D-aspartate selective glutamate receptor activity | IEA | molecular_function |
| GO:0005234 | Extracellular-glutamate-gated ion channel activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008344 | Adult locomotory behavior | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0051930 | Regulation of sensory perception of pain | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5721633677 | 0.6907997872 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0405481550 |
| GSE13712_SHEAR | Down | -0.2149667106 |
| GSE13712_STATIC | Up | 0.1357275268 |
| GSE19018 | Down | -0.0453268289 |
| GSE19899_A1 | Down | -0.0472499261 |
| GSE19899_A2 | Up | 0.1266239347 |
| PubMed_21979375_A1 | Up | 0.0848106172 |
| PubMed_21979375_A2 | Down | -0.2110109824 |
| GSE35957 | Up | 0.0537318817 |
| GSE36640 | Down | -0.2590429640 |
| GSE54402 | Down | -0.0128569600 |
| GSE9593 | Up | 0.0659387968 |
| GSE43922 | Up | 0.0295777780 |
| GSE24585 | Up | 0.3090960159 |
| GSE37065 | Down | -0.0586207699 |
| GSE28863_A1 | Up | 0.0535626126 |
| GSE28863_A2 | Up | 0.0050259662 |
| GSE28863_A3 | Up | 0.3489767733 |
| GSE28863_A4 | Down | -0.0238651748 |
| GSE48662 | Down | -0.1524638865 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Glutamic Acid | DB00142 | NUTR00027 |
| Pethidine | DB00454 | APRD00074 |
| Tenocyclidine | DB01520 | - |
| Acamprosate | DB00659 | APRD00661 |
| Gavestinel | DB06741 | - |
| Atomoxetine | DB00289 | APRD00614 |
| Pentobarbital | DB00312 | APRD01174 |
| Gabapentin | DB00996 | APRD00015 |
| Dehydroepiandrosterone | DB01708 | EXPT00519 | DB06593 |
| Milnacipran | DB04896 | - |
| Ketobemidone | DB06738 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017316 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
