HCSGD entry for GRIK4

1. General information

Official gene symbolGRIK4
Entrez ID2900
Gene full nameglutamate receptor, ionotropic, kainate 4
Other gene symbolsEAA1 GRIK GluK4 KA1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005234Extracellular-glutamate-gated ion channel activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0007215Glutamate receptor signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0015277Kainate selective glutamate receptor activityTASmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0030425DendriteIEAcellular_component
GO:0031960Response to corticosteroidIEAbiological_process
GO:0032983Kainate selective glutamate receptor complexIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0035235Ionotropic glutamate receptor signaling pathwayTASbiological_process
GO:0042734Presynaptic membraneIEAcellular_component
GO:0043195Terminal boutonIEAcellular_component
GO:0043204PerikaryonIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56100500740.79644126360.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1033576335
GSE13712_SHEARDown-0.0449760559
GSE13712_STATICDown-0.1032089222
GSE19018Up0.1972579046
GSE19899_A1Up0.0425340650
GSE19899_A2Down-0.0229049326
PubMed_21979375_A1Up0.2270465241
PubMed_21979375_A2Up0.0411155234
GSE35957Up0.0072476880
GSE36640Up0.0492656423
GSE54402Up0.0893178559
GSE9593Up0.0185721485
GSE43922Up0.0385423999
GSE24585Up0.0791433435
GSE37065Down-0.0983132254
GSE28863_A1Up0.0617105468
GSE28863_A2Down-0.3949892675
GSE28863_A3Up0.3042299123
GSE28863_A4Up0.0162259611
GSE48662Up0.0303198592

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017088MicroarrayFunctional MTI (Weak)18185580
hsa-miR-196a-5pMIMAT0000226MIRT048273CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.