HCSGD entry for ABR

1. General information

Official gene symbolABR
Entrez ID29
Gene full nameactive BCR-related
Other gene symbolsMDB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005096GTPase activator activityIEA TASmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005829CytosolIEA TAScellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007165Signal transductionIEAbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007420Brain developmentIEAbiological_process
GO:0030036Actin cytoskeleton organizationIEAbiological_process
GO:0030336Negative regulation of cell migrationIEAbiological_process
GO:0030675Rac GTPase activator activityIEAmolecular_function
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0043065Positive regulation of apoptotic processTASbiological_process
GO:0043314Negative regulation of neutrophil degranulationIEAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0050728Negative regulation of inflammatory responseIEAbiological_process
GO:0050766Positive regulation of phagocytosisIEAbiological_process
GO:0050885Neuromuscular process controlling balanceIEAbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02507834050.97897708290.37282093421.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0273431129
GSE13712_SHEARDown-0.2701267245
GSE13712_STATICDown-0.1517838072
GSE19018Up0.2489246034
GSE19899_A1Up0.2408517106
GSE19899_A2Up0.2717284335
PubMed_21979375_A1Up0.2903515194
PubMed_21979375_A2Up0.5045341776
GSE35957Down-0.0438071477
GSE36640Up0.1042024006
GSE54402Up0.6077454862
GSE9593Up1.0849004856
GSE43922Up0.2281537433
GSE24585Up0.2487940495
GSE37065Up0.3131327059
GSE28863_A1Down-0.0050486715
GSE28863_A2Up0.2877698869
GSE28863_A3Up0.1518468955
GSE28863_A4Up0.0585285489
GSE48662Down-0.0163383491

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-3pMIMAT0004950MIRT037178CLASHFunctional MTI (Weak)23622248
hsa-miR-93-3pMIMAT0004509MIRT038901CLASHFunctional MTI (Weak)23622248
hsa-miR-92b-3pMIMAT0003218MIRT040702CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-5pMIMAT0000072MIRT050728CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.