HCSGD entry for KLF15


1. General information

Official gene symbolKLF15
Entrez ID28999
Gene full nameKruppel-like factor 15
Other gene symbolsKKLF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionICmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006366Transcription from RNA polymerase II promoterICbiological_process
GO:0010001Glial cell differentiationIEAbiological_process
GO:0015758Glucose transportIEAbiological_process
GO:0044212Transcription regulatory region DNA bindingISSmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIMPbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0072112Glomerular visceral epithelial cell differentiationISSbiological_process
GO:1901653Cellular response to peptideIEAbiological_process
GO:2000757Negative regulation of peptidyl-lysine acetylationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78719939590.49659421370.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0234454900
GSE13712_SHEARDown-0.1773485796
GSE13712_STATICDown-0.5715952653
GSE19018Up0.1411274557
GSE19899_A1Down-0.0318290714
GSE19899_A2Up0.0927182338
PubMed_21979375_A1Down-0.0801081892
PubMed_21979375_A2Down-0.0331372029
GSE35957Up0.2073570237
GSE36640Down-0.0159661438
GSE54402Up0.0663740656
GSE9593Down-0.0326298044
GSE43922Up0.0284448071
GSE24585Down-0.1336492863
GSE37065Down-0.0708245611
GSE28863_A1Down-0.1877099784
GSE28863_A2Down-0.0440022367
GSE28863_A3Up0.2371373838
GSE28863_A4Up0.1823047191
GSE48662Down-0.0365890482

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-133bMIMAT0000770NAhsa-miR-133b{Western blot}{overexpression}19720047
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.