HCSGD entry for OSTM1
1. General information
| Official gene symbol | OSTM1 |
|---|---|
| Entrez ID | 28962 |
| Gene full name | osteopetrosis associated transmembrane protein 1 |
| Other gene symbols | GIPN GL OPTB5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005765 | Lysosomal membrane | TAS | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030316 | Osteoclast differentiation | IEA | biological_process |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0016202994 | 0.9353221268 | 0.1079693671 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3469400838 |
| GSE13712_SHEAR | Down | -0.4241132070 |
| GSE13712_STATIC | Up | 0.0543804638 |
| GSE19018 | Up | 0.1501961930 |
| GSE19899_A1 | Up | 0.7773652680 |
| GSE19899_A2 | Up | 1.1992153447 |
| PubMed_21979375_A1 | Up | 1.2308286590 |
| PubMed_21979375_A2 | Up | 1.4962223021 |
| GSE35957 | Up | 0.9521440925 |
| GSE36640 | Up | 2.1326983998 |
| GSE54402 | Up | 0.2626280976 |
| GSE9593 | Up | 0.6118270744 |
| GSE43922 | Up | 0.5992523971 |
| GSE24585 | Up | 0.3606770965 |
| GSE37065 | Up | 0.3810124508 |
| GSE28863_A1 | Down | -0.5904002696 |
| GSE28863_A2 | Up | 0.7552460218 |
| GSE28863_A3 | Down | -0.4771855462 |
| GSE28863_A4 | Down | -0.2859513915 |
| GSE48662 | Up | 0.3614832826 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-140-5p | MIMAT0000431 | MIRT007373 | Luciferase reporter assay | Functional MTI | 23389033 |
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016070 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT020467 | Microarray | Functional MTI (Weak) | 17242205 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT021288 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029214 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052255 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
