HCSGD entry for DCPS

1. General information

Official gene symbolDCPS
Entrez ID28960
Gene full namedecapping enzyme, scavenger
Other gene symbolsDCS1 HINT-5 HINT5 HSL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000288Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decayTASbiological_process
GO:0000290Deadenylation-dependent decapping of nuclear-transcribed mRNAIEAbiological_process
GO:0000340RNA 7-methylguanosine cap bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0010467Gene expressionTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0036245Cellular response to menadioneIDAbiological_process
GO:0043069Negative regulation of programmed cell deathIDAbiological_process
GO:0043928Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decayTASbiological_process
GO:0045292MRNA cis splicing, via spliceosomeIDAbiological_process
GO:0050072M7G(5')pppN diphosphatase activityIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.43148088980.12741969910.99999024730.6873978069

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0146824565
GSE13712_SHEARDown-0.8608959436
GSE13712_STATICDown-0.1879036457
GSE19018Down-0.0360452903
GSE19899_A1Down-0.1959773023
GSE19899_A2Up0.7567956311
PubMed_21979375_A1Up0.8030095147
PubMed_21979375_A2Down-0.0748371919
GSE35957Down-0.8119834588
GSE36640Down-1.3332800527
GSE54402Up0.7059348668
GSE9593Down-0.3879938081
GSE43922Up0.1651586823
GSE24585Up0.0528973201
GSE37065Down-0.0579259647
GSE28863_A1Down-0.0394013895
GSE28863_A2Up0.0094953469
GSE28863_A3Up0.0120127986
GSE28863_A4Up0.1500895390
GSE48662Down-0.2966809156

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

7-Methyl-GpppaDB01649 EXPT01652
7n-Methyl-8-Hydroguanosine-5'-DiphosphateDB01960 EXPT02090 | EXPT02143
N7-Methyl-Guanosine-5'-MonophosphateDB03593 EXPT01539
7-methyl-guanosine-5'-triphosphate-5'-guanosineDB03958 EXPT01655
5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamineDB07642 -
5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamineDB07643 -
5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamineDB07644 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT041500CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.