HCSGD entry for GRIA3

1. General information

Official gene symbolGRIA3
Entrez ID2892
Gene full nameglutamate receptor, ionotropic, AMPA 3
Other gene symbolsGLUR-C GLUR-K3 GLUR3 GLURC GluA3 MRX94
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004970Ionotropic glutamate receptor activityIEAmolecular_function
GO:0004971Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activityIDAmolecular_function
GO:0005234Extracellular-glutamate-gated ion channel activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0007215Glutamate receptor signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0032281Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complexISScellular_component
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0035235Ionotropic glutamate receptor signaling pathwayIDAbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41121978270.31024407890.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0864238249
GSE13712_SHEARDown-0.0755507823
GSE13712_STATICDown-0.0562916291
GSE19018Down-0.0142867863
GSE19899_A1Up0.0586603340
GSE19899_A2Up0.0336467913
PubMed_21979375_A1Up0.0271289345
PubMed_21979375_A2Up0.0371920187
GSE35957Up1.0594690804
GSE36640Up0.0020718429
GSE54402Up0.0759274405
GSE9593Up0.2462918643
GSE43922Up0.0120147115
GSE24585Down-0.3936927086
GSE37065Up0.1167073976
GSE28863_A1Up0.2454366126
GSE28863_A2Up0.4449778774
GSE28863_A3Down-0.7082603610
GSE28863_A4Down-0.4975001502
GSE48662Down-0.1234926457

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027
LithiumDB01356 -
AniracetamDB04599 -
TalampanelDB04982 -
CX717DB05047 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.