HCSGD entry for GRIA2

1. General information

Official gene symbolGRIA2
Entrez ID2891
Gene full nameglutamate receptor, ionotropic, AMPA 2
Other gene symbolsGLUR2 GLURB GluA2 GluR-K2 HBGR2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004970Ionotropic glutamate receptor activityIDA IEAmolecular_function
GO:0004971Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activityISSmolecular_function
GO:0005215Transporter activityIEAmolecular_function
GO:0005234Extracellular-glutamate-gated ion channel activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneISScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007268Synaptic transmissionIEA TASbiological_process
GO:0008021Synaptic vesicleIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0032281Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complexIEA ISScellular_component
GO:0034220Ion transmembrane transportIDA ISS TASbiological_process
GO:0035235Ionotropic glutamate receptor signaling pathwayIDAbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportIDA ISS TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91126264200.67786022570.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0557081913
GSE13712_SHEARDown-0.0584527421
GSE13712_STATICDown-0.0506133299
GSE19018Down-0.0323880293
GSE19899_A1Up0.0725137654
GSE19899_A2Down-0.1632260640
PubMed_21979375_A1Down-0.0326906772
PubMed_21979375_A2Down-0.1422928600
GSE35957Up0.0622850932
GSE36640Up0.0782914346
GSE54402Up0.0378576653
GSE9593Down-0.0550592493
GSE43922Up0.0170389295
GSE24585Up0.1287155582
GSE37065Down-0.1438222390
GSE28863_A1Up0.0178866267
GSE28863_A2Up0.0762941488
GSE28863_A3Up0.1310168475
GSE28863_A4Down-0.0062545119
GSE48662Down-0.0449995312

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-181b-5pMIMAT0000257MIRT003035Luciferase assay/RT-PCR//Reporter assay;OtherFunctional MTI18184693
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-181b-5pMIMAT00002571hsa-miR-181b18184693
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.