HCSGD entry for GPS2
1. General information
| Official gene symbol | GPS2 |
|---|---|
| Entrez ID | 2874 |
| Gene full name | G protein pathway suppressor 2 |
| Other gene symbols | AMF-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0000188 | Inactivation of MAPK activity | TAS | biological_process |
| GO:0003714 | Transcription corepressor activity | IDA | molecular_function |
| GO:0005095 | GTPase inhibitor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0007049 | Cell cycle | TAS | biological_process |
| GO:0007254 | JNK cascade | TAS | biological_process |
| GO:0017053 | Transcriptional repressor complex | IDA | cellular_component |
| GO:0046329 | Negative regulation of JNK cascade | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8886352532 | 0.1194891493 | 0.9999902473 | 0.6639379143 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3314240317 |
| GSE13712_SHEAR | Down | -0.2132202610 |
| GSE13712_STATIC | Up | 0.0018391275 |
| GSE19018 | Down | -0.1253800686 |
| GSE19899_A1 | Down | -0.9519930254 |
| GSE19899_A2 | Down | -0.6599428401 |
| PubMed_21979375_A1 | Up | 0.1992176715 |
| PubMed_21979375_A2 | Down | -0.0335463296 |
| GSE35957 | Down | -0.3550653493 |
| GSE36640 | Down | -0.5617219575 |
| GSE54402 | Down | -0.2815838731 |
| GSE9593 | Up | 0.0774765990 |
| GSE43922 | Up | 0.0531902186 |
| GSE24585 | Up | 0.2796987127 |
| GSE37065 | Down | -0.0387516696 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0651353956 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
