HCSGD entry for SH3PXD2B

1. General information

Official gene symbolSH3PXD2B
Entrez ID285590
Gene full nameSH3 and PX domains 2B
Other gene symbolsFAD49 FTHS HOFI KIAA1295 TKS4 TSK4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentIMPbiological_process
GO:0001654Eye developmentIMPbiological_process
GO:0002102PodosomeISScellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmISScellular_component
GO:0006801Superoxide metabolic processIDAbiological_process
GO:0007154Cell communicationIEAbiological_process
GO:0007507Heart developmentIMPbiological_process
GO:0010314Phosphatidylinositol-5-phosphate bindingISSmolecular_function
GO:0022617Extracellular matrix disassemblyIMPbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0030154Cell differentiationIEAbiological_process
GO:0032266Phosphatidylinositol-3-phosphate bindingISSmolecular_function
GO:0035091Phosphatidylinositol bindingIEAmolecular_function
GO:0042169SH2 domain bindingISSmolecular_function
GO:0042995Cell projectionIEAcellular_component
GO:0045600Positive regulation of fat cell differentiationIEAbiological_process
GO:0060348Bone developmentIMPbiological_process
GO:0060612Adipose tissue developmentISSbiological_process
GO:0070273Phosphatidylinositol-4-phosphate bindingIEAmolecular_function
GO:0071800Podosome assemblyISSbiological_process
GO:0072657Protein localization to membraneIDAbiological_process
GO:0080025Phosphatidylinositol-3,5-bisphosphate bindingISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04867173360.75678930890.48642702091.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0446729519
GSE13712_SHEARDown-0.2175723544
GSE13712_STATICUp0.0072867815
GSE19018Down-0.4799856461
GSE19899_A1Up0.1168976537
GSE19899_A2Down-0.1052772806
PubMed_21979375_A1Up0.3181369117
PubMed_21979375_A2Up0.8690543886
GSE35957Down-0.1746243004
GSE36640Down-0.2359727543
GSE54402Up0.6487060938
GSE9593Up0.1666103097
GSE43922Up0.2687352355
GSE24585Up0.0554012243
GSE37065Up0.2797172743
GSE28863_A1Up1.0955762312
GSE28863_A2Up1.0009800952
GSE28863_A3Up0.1338031347
GSE28863_A4Down-0.1803161116
GSE48662Down-0.3358241091

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT001847MicroarrayFunctional MTI (Weak)18668037
hsa-miR-1MIMAT0000416MIRT001847MicroarrayFunctional MTI (Weak)15685193
hsa-miR-335-5pMIMAT0000765MIRT018269MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.