HCSGD entry for DLL1

1. General information

Official gene symbolDLL1
Entrez ID28514
Gene full namedelta-like 1 (Drosophila)
Other gene symbolsDELTA1 DL1 Delta
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001709Cell fate determinationNASbiological_process
GO:0001757Somite specificationIEAbiological_process
GO:0001947Heart loopingISSbiological_process
GO:0005112Notch bindingIPImolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionNAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0007219Notch signaling pathwayIMP NAS TASbiological_process
GO:0007220Notch receptor processingTASbiological_process
GO:0007267Cell-cell signalingIEAbiological_process
GO:0007368Determination of left/right symmetryISSbiological_process
GO:0007386Compartment pattern specificationIEAbiological_process
GO:0030097HemopoiesisNASbiological_process
GO:0030154Cell differentiationTASbiological_process
GO:0030155Regulation of cell adhesionTASbiological_process
GO:0031410Cytoplasmic vesicleIEAcellular_component
GO:0045608Negative regulation of auditory receptor cell differentiationIEAbiological_process
GO:0045638Negative regulation of myeloid cell differentiationIEAbiological_process
GO:0045747Positive regulation of Notch signaling pathwayIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0048839Inner ear developmentIEAbiological_process
GO:0070986Left/right axis specificationIEAbiological_process
GO:0072014Proximal tubule developmentIEAbiological_process
GO:0072070Loop of Henle developmentIEAbiological_process
GO:0097150Neuronal stem cell maintenanceIEPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66838787280.30612156450.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0921640340
GSE13712_SHEARDown-2.3662099306
GSE13712_STATICDown-0.9280293967
GSE19018Up0.0206746016
GSE19899_A1Up0.2512210002
GSE19899_A2Up0.3026919080
PubMed_21979375_A1Up0.0383888434
PubMed_21979375_A2Up0.1026099745
GSE35957Down-0.1327516566
GSE36640Up0.0107428879
GSE54402Up0.2569579589
GSE9593Up0.0132199913
GSE43922Up0.0543995264
GSE24585Down-0.0437758181
GSE37065Down-0.0204055887
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0084926237

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT001757Luciferase reporter assayFunctional MTI14697198
hsa-miR-34a-5pMIMAT0000255MIRT001757Luciferase reporter assayFunctional MTI19461653
hsa-miR-34a-5pMIMAT0000255MIRT001757Luciferase reporter assayFunctional MTI20144220
hsa-miR-335-5pMIMAT0000765MIRT017844MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-34a-5pMIMAT00002551hsa-miR-34a14697198
hsa-miR-34a-5pMIMAT00002552hsa-miR-34a14697198
hsa-miR-34a-5pMIMAT00002553hsa-miR-34a14697198
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.