HCSGD entry for NEK8
1. General information
| Official gene symbol | NEK8 |
|---|---|
| Entrez ID | 284086 |
| Gene full name | NIMA-related kinase 8 |
| Other gene symbols | JCK NEK12A NPHP9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0009887 | Organ morphogenesis | IMP | biological_process |
| GO:0035330 | Regulation of hippo signaling | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0072372 | Primary cilium | IEA ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4593243342 | 0.8752289275 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0980360091 |
| GSE13712_SHEAR | Up | 0.2291493469 |
| GSE13712_STATIC | Up | 0.2894997247 |
| GSE19018 | Down | -0.0967195014 |
| GSE19899_A1 | Down | -0.0992773653 |
| GSE19899_A2 | Up | 0.2787733537 |
| PubMed_21979375_A1 | Down | -0.1480733771 |
| PubMed_21979375_A2 | Up | 0.1064594163 |
| GSE35957 | Down | -0.0411997059 |
| GSE36640 | Up | 0.1029386870 |
| GSE54402 | Down | -0.1389582734 |
| GSE9593 | Down | -0.0937116572 |
| GSE43922 | Up | 0.0545749012 |
| GSE24585 | Up | 0.1809154910 |
| GSE37065 | Up | 0.0547951631 |
| GSE28863_A1 | Up | 0.0420659211 |
| GSE28863_A2 | Down | -0.0493952998 |
| GSE28863_A3 | Up | 0.2855716521 |
| GSE28863_A4 | Up | 0.1471277768 |
| GSE48662 | Up | 0.0450740764 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
