HCSGD entry for KSR2
1. General information
| Official gene symbol | KSR2 |
|---|---|
| Entrez ID | 283455 |
| Gene full name | kinase suppressor of ras 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005078 | MAP-kinase scaffold activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0019722 | Calcium-mediated signaling | IEA | biological_process |
| GO:0031434 | Mitogen-activated protein kinase kinase binding | IEA | molecular_function |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0043410 | Positive regulation of MAPK cascade | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5360419779 | 0.8734331218 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1103819752 |
| GSE13712_SHEAR | Down | -0.1765262576 |
| GSE13712_STATIC | Down | -0.5217947001 |
| GSE19018 | Up | 0.1441534837 |
| GSE19899_A1 | Up | 0.1326344292 |
| GSE19899_A2 | Up | 0.1687915538 |
| PubMed_21979375_A1 | Down | -0.0647237567 |
| PubMed_21979375_A2 | Down | -0.0291791440 |
| GSE35957 | Up | 0.0441033310 |
| GSE36640 | Up | 0.1437084791 |
| GSE54402 | Up | 0.0112761870 |
| GSE9593 | Up | 0.0851224346 |
| GSE43922 | Up | 0.0352540456 |
| GSE24585 | Up | 0.0107323432 |
| GSE37065 | Down | -0.1431940198 |
| GSE28863_A1 | Up | 0.2046785981 |
| GSE28863_A2 | Up | 0.2124242719 |
| GSE28863_A3 | Up | 0.2886678228 |
| GSE28863_A4 | Up | 0.0026874050 |
| GSE48662 | Down | -0.0628338974 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-940 | MIMAT0004983 | MIRT036596 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
