HCSGD entry for P4HA3
1. General information
| Official gene symbol | P4HA3 |
|---|---|
| Entrez ID | 283208 |
| Gene full name | prolyl 4-hydroxylase, alpha polypeptide III |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004656 | Procollagen-proline 4-dioxygenase activity | IEA | molecular_function |
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005581 | Collagen | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | IEA | cellular_component |
| GO:0016702 | Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | IEA | molecular_function |
| GO:0031418 | L-ascorbic acid binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9633996923 | 0.0072520421 | 0.9999902473 | 0.1699997329 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3381503109 |
| GSE13712_SHEAR | Down | -0.3396510860 |
| GSE13712_STATIC | Down | -0.7135320629 |
| GSE19018 | Down | -0.3720560512 |
| GSE19899_A1 | Down | -0.0806987936 |
| GSE19899_A2 | Down | -1.1851935584 |
| PubMed_21979375_A1 | Down | -0.7147479522 |
| PubMed_21979375_A2 | Down | -0.8277254280 |
| GSE35957 | Down | -0.3338261957 |
| GSE36640 | Down | -1.1212738782 |
| GSE54402 | Down | -0.8494718359 |
| GSE9593 | Down | -0.2300212369 |
| GSE43922 | Up | 0.0231365364 |
| GSE24585 | Up | 0.1435019399 |
| GSE37065 | Up | 0.6735182405 |
| GSE28863_A1 | Down | -0.2496488674 |
| GSE28863_A2 | Up | 0.2383644152 |
| GSE28863_A3 | Up | 0.1318673685 |
| GSE28863_A4 | Down | -0.2179700727 |
| GSE48662 | Up | 0.2022789985 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018485 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022868 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
