HCSGD entry for GNS
1. General information
| Official gene symbol | GNS |
|---|---|
| Entrez ID | 2799 |
| Gene full name | glucosamine (N-acetyl)-6-sulfatase |
| Other gene symbols | G6S |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006027 | Glycosaminoglycan catabolic process | TAS | biological_process |
| GO:0008449 | N-acetylglucosamine-6-sulfatase activity | IEA | molecular_function |
| GO:0008484 | Sulfuric ester hydrolase activity | IDA | molecular_function |
| GO:0030203 | Glycosaminoglycan metabolic process | IEA TAS | biological_process |
| GO:0042339 | Keratan sulfate metabolic process | TAS | biological_process |
| GO:0042340 | Keratan sulfate catabolic process | TAS | biological_process |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0472736636 | 0.9369401505 | 0.4810151913 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0860346059 |
| GSE13712_SHEAR | Up | 0.1235442085 |
| GSE13712_STATIC | Up | 0.0304637789 |
| GSE19018 | Up | 0.0478004497 |
| GSE19899_A1 | Down | -0.0040092436 |
| GSE19899_A2 | Up | 0.5130154788 |
| PubMed_21979375_A1 | Down | -0.0823049538 |
| PubMed_21979375_A2 | Up | 0.4770847373 |
| GSE35957 | Up | 0.3011687433 |
| GSE36640 | Up | 0.4338184540 |
| GSE54402 | Down | -0.3254350483 |
| GSE9593 | Up | 0.9814145235 |
| GSE43922 | Up | 0.0253413690 |
| GSE24585 | Up | 0.5919468717 |
| GSE37065 | Up | 0.2862384294 |
| GSE28863_A1 | Up | 0.1232507098 |
| GSE28863_A2 | Up | 0.4160057940 |
| GSE28863_A3 | Down | -0.5351081152 |
| GSE28863_A4 | Up | 0.0857690521 |
| GSE48662 | Up | 0.1480110260 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018960 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027186 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-484 | MIMAT0002174 | MIRT042074 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046266 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-107 | MIMAT0000104 | MIRT048309 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
