HCSGD entry for GNRHR
1. General information
| Official gene symbol | GNRHR |
|---|---|
| Entrez ID | 2798 |
| Gene full name | gonadotropin-releasing hormone receptor |
| Other gene symbols | GNRHR1 GRHR HH7 LHRHR LRHR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004968 | Gonadotropin-releasing hormone receptor activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0097211 | Cellular response to gonadotropin-releasing hormone | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6897889290 | 0.8310819498 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0186155042 |
| GSE13712_SHEAR | Down | -0.0071633745 |
| GSE13712_STATIC | Down | -0.0540951962 |
| GSE19018 | Up | 0.1140721579 |
| GSE19899_A1 | Up | 0.1829655148 |
| GSE19899_A2 | Up | 0.0424895584 |
| PubMed_21979375_A1 | Up | 0.1612015217 |
| PubMed_21979375_A2 | Up | 0.2175431151 |
| GSE35957 | Up | 0.0918304125 |
| GSE36640 | Down | -0.0481070862 |
| GSE54402 | Down | -0.0470977774 |
| GSE9593 | Down | -0.0272244557 |
| GSE43922 | Up | 0.0203348082 |
| GSE24585 | Up | 0.0849982918 |
| GSE37065 | Up | 0.0100915867 |
| GSE28863_A1 | Down | -0.2187877975 |
| GSE28863_A2 | Down | -0.0387768027 |
| GSE28863_A3 | Up | 0.0227318625 |
| GSE28863_A4 | Down | -0.0557074491 |
| GSE48662 | Up | 0.1503646016 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Goserelin | DB00014 | BTD00113 | BIOD00113 |
| Cetrorelix | DB00050 | BTD00115 | APRD00686 | BIOD00115 |
| Abarelix | DB00106 | BTD00051 | BIOD00051 |
| Gonadorelin | DB00644 | APRD01001 |
| Nafarelin | DB00666 | APRD01129 |
| Danazol | DB01406 | - |
| NBI-56418 | DB05694 | - |
| Degarelix | DB06699 | - |
| Buserelin | DB06719 | - |
| Ganirelix | DB06785 | - |
| Triptorelin | DB06825 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022748 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023851 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029569 | Microarray | Functional MTI (Weak) | 19088304 |
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