HCSGD entry for GNRHR


1. General information

Official gene symbolGNRHR
Entrez ID2798
Gene full namegonadotropin-releasing hormone receptor
Other gene symbolsGNRHR1 GRHR HH7 LHRHR LRHR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004968Gonadotropin-releasing hormone receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0097211Cellular response to gonadotropin-releasing hormoneTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.68978892900.83108194980.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0186155042
GSE13712_SHEARDown-0.0071633745
GSE13712_STATICDown-0.0540951962
GSE19018Up0.1140721579
GSE19899_A1Up0.1829655148
GSE19899_A2Up0.0424895584
PubMed_21979375_A1Up0.1612015217
PubMed_21979375_A2Up0.2175431151
GSE35957Up0.0918304125
GSE36640Down-0.0481070862
GSE54402Down-0.0470977774
GSE9593Down-0.0272244557
GSE43922Up0.0203348082
GSE24585Up0.0849982918
GSE37065Up0.0100915867
GSE28863_A1Down-0.2187877975
GSE28863_A2Down-0.0387768027
GSE28863_A3Up0.0227318625
GSE28863_A4Down-0.0557074491
GSE48662Up0.1503646016

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GoserelinDB00014 BTD00113 | BIOD00113
CetrorelixDB00050 BTD00115 | APRD00686 | BIOD00115
AbarelixDB00106 BTD00051 | BIOD00051
GonadorelinDB00644 APRD01001
NafarelinDB00666 APRD01129
DanazolDB01406 -
NBI-56418DB05694 -
DegarelixDB06699 -
BuserelinDB06719 -
GanirelixDB06785 -
TriptorelinDB06825 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022748MicroarrayFunctional MTI (Weak)18668037
hsa-miR-1MIMAT0000416MIRT023851MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT029569MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.