HCSGD entry for AMY2A
1. General information
| Official gene symbol | AMY2A |
|---|---|
| Entrez ID | 279 |
| Gene full name | amylase, alpha 2A (pancreatic) |
| Other gene symbols | AMY2 AMY2B PA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0004556 | Alpha-amylase activity | IDA | molecular_function |
| GO:0005509 | Calcium ion binding | IDA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | IEA TAS | biological_process |
| GO:0016052 | Carbohydrate catabolic process | IDA | biological_process |
| GO:0031404 | Chloride ion binding | IDA | molecular_function |
| GO:0043169 | Cation binding | IEA | molecular_function |
| GO:0044245 | Polysaccharide digestion | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9476606094 | 0.6911800805 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.0700376409 |
| GSE28863_A2 | Up | 0.0767460626 |
| GSE28863_A3 | Up | 0.0466725915 |
| GSE28863_A4 | Down | -0.2600806697 |
| GSE48662 | - | - |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Acarbose | DB00284 | APRD00656 |
| Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam | DB01922 | EXPT01998 |
| N-[4-Hydroxymethyl-Cyclohexan-6-Yl-1,2,3-Triol]-4,6-Dideoxy-4-Aminoglucopyranoside | DB02218 | EXPT00405 |
| Beta-D-Glucose | DB02379 | EXPT00685 | EXPT00455 | EXPT01603 |
| 4-O-(4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Beta-D-Lyxo-Hexopyranosyl)-Alpha-D-Erythro-Hexopyranose | DB02889 | EXPT00191 |
| Pyroglutamic Acid | DB03088 | EXPT00247 |
| 5-Hydroxymethyl-Chonduritol | DB03092 | EXPT01756 |
| 4,6-Dideoxy-4-Amino-Alpha-D-Glucose | DB03439 | EXPT00456 |
| 4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Alpha-D-Lyxo-Hexopyranosyl-(1->4)-Alpha-D-Threo-Hexopyranosyl-(1->6)-Alpha-L-Threo-Hexopyranose | DB03495 | EXPT01820 |
| 6-Deoxy-Alpha-D-Glucose | DB03773 | EXPT01536 |
| Acarbose Derived Hexasaccharide | DB03971 | EXPT00291 |
| 4-O-(4,6-Dideoxy-4-{[4-[(4-O-Hexopyranosylhexopyranosyl)Oxy]-5,6-Dihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}Hexopyranosyl)Hexopyranose | DB04453 | EXPT00557 |
| 4,6-DIDEOXY-4-{[4-[(4-O-HEXOPYRANOSYLHEXOPYRANOSYL)OXY]-5,6-DIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}HEXOPYRANOSYL-(1->4)HEXOPYRANOSYL-(1->4)HEXOPYRANOSE | DB04618 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 11756559 | The majority of these tumors were found in the pancreas, pituitary, brain, mammary tissue, and skin |
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