HCSGD entry for GNAZ
1. General information
| Official gene symbol | GNAZ |
|---|---|
| Entrez ID | 2781 |
| Gene full name | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IBA | molecular_function |
| GO:0004871 | Signal transducer activity | IBA | molecular_function |
| GO:0005057 | Receptor signaling protein activity | TAS | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005635 | Nuclear envelope | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0005834 | Heterotrimeric G-protein complex | IBA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007188 | Adenylate cyclase-modulating G-protein coupled receptor signaling pathway | IBA | biological_process |
| GO:0007193 | Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0031234 | Extrinsic component of cytoplasmic side of plasma membrane | IBA | cellular_component |
| GO:0031683 | G-protein beta/gamma-subunit complex binding | IBA | molecular_function |
| GO:0031821 | G-protein coupled serotonin receptor binding | IBA | molecular_function |
| GO:0035556 | Intracellular signal transduction | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5153997758 | 0.1303474184 | 0.9999902473 | 0.6949310107 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1106609243 |
| GSE13712_SHEAR | Down | -1.8923937454 |
| GSE13712_STATIC | Up | 0.1536415558 |
| GSE19018 | Down | -0.2564877482 |
| GSE19899_A1 | Down | -0.0840311400 |
| GSE19899_A2 | Up | 0.0053931686 |
| PubMed_21979375_A1 | Down | -0.4218724858 |
| PubMed_21979375_A2 | Down | -0.3995956616 |
| GSE35957 | Down | -0.0517949680 |
| GSE36640 | Down | -0.2682156451 |
| GSE54402 | Up | 0.3035724795 |
| GSE9593 | Up | 0.0678946199 |
| GSE43922 | Up | 0.0545814397 |
| GSE24585 | Down | -0.5074462092 |
| GSE37065 | Up | 0.1062890980 |
| GSE28863_A1 | Down | -0.0889474216 |
| GSE28863_A2 | Up | 0.1863603575 |
| GSE28863_A3 | Up | 0.5221204292 |
| GSE28863_A4 | Up | 0.0148207974 |
| GSE48662 | Up | 0.6428959303 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046159 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
