HCSGD entry for GNAT2
1. General information
| Official gene symbol | GNAT2 |
|---|---|
| Entrez ID | 2780 |
| Gene full name | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| Other gene symbols | ACHM4 GNATC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001580 | Detection of chemical stimulus involved in sensory perception of bitter taste | IBA | biological_process |
| GO:0001664 | G-protein coupled receptor binding | IBA | molecular_function |
| GO:0001750 | Photoreceptor outer segment | IDA ISS | cellular_component |
| GO:0001917 | Photoreceptor inner segment | IDA | cellular_component |
| GO:0003924 | GTPase activity | IBA | molecular_function |
| GO:0004871 | Signal transducer activity | IBA | molecular_function |
| GO:0005525 | GTP binding | NAS | molecular_function |
| GO:0005834 | Heterotrimeric G-protein complex | IBA NAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | NAS | biological_process |
| GO:0007188 | Adenylate cyclase-modulating G-protein coupled receptor signaling pathway | IBA | biological_process |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | IEA | biological_process |
| GO:0007601 | Visual perception | NAS | biological_process |
| GO:0007602 | Phototransduction | NAS | biological_process |
| GO:0008020 | G-protein coupled photoreceptor activity | NAS | molecular_function |
| GO:0009642 | Response to light intensity | IEA | biological_process |
| GO:0031234 | Extrinsic component of cytoplasmic side of plasma membrane | IBA | cellular_component |
| GO:0031683 | G-protein beta/gamma-subunit complex binding | IBA | molecular_function |
| GO:0042622 | Photoreceptor outer segment membrane | ISS | cellular_component |
| GO:0046549 | Retinal cone cell development | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0050908 | Detection of light stimulus involved in visual perception | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5215930246 | 0.6889510771 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0756216720 |
| GSE13712_SHEAR | Down | -0.2857307280 |
| GSE13712_STATIC | Down | -0.1243955584 |
| GSE19018 | Up | 0.0763200856 |
| GSE19899_A1 | Up | 0.1205161540 |
| GSE19899_A2 | Up | 0.1843788626 |
| PubMed_21979375_A1 | Up | 0.7183101820 |
| PubMed_21979375_A2 | Up | 0.2657017247 |
| GSE35957 | Up | 0.0933353440 |
| GSE36640 | Up | 0.5495676896 |
| GSE54402 | Up | 0.2527941989 |
| GSE9593 | Up | 0.0087976199 |
| GSE43922 | Up | 0.0219377356 |
| GSE24585 | Down | -0.1170332212 |
| GSE37065 | Down | -0.0956703916 |
| GSE28863_A1 | Up | 0.0083750244 |
| GSE28863_A2 | Down | -0.1186611876 |
| GSE28863_A3 | Down | -0.0395730627 |
| GSE28863_A4 | Down | -0.2460174071 |
| GSE48662 | Up | 0.0397222136 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-9-5p | MIMAT0000441 | MIRT021422 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-1 | MIMAT0000416 | MIRT023994 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
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