HCSGD entry for GNAT1

1. General information

Official gene symbol	GNAT1
Entrez ID	2779
Gene full name	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
Other gene symbols	CSNBAD3 GBT1 GNATR
Links to Entrez Gene	Links to Entrez Gene

2. Neighbors in the network

This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID	GO term	Evidence	Category
GO:0000035	Acyl binding	ISS	molecular_function
GO:0001580	Detection of chemical stimulus involved in sensory perception of bitter taste	IBA IEA	biological_process
GO:0001664	G-protein coupled receptor binding	IBA	molecular_function
GO:0001750	Photoreceptor outer segment	IDA IEA	cellular_component
GO:0001917	Photoreceptor inner segment	IDA IEA	cellular_component
GO:0003924	GTPase activity	IBA IEA NAS TAS	molecular_function
GO:0004871	Signal transducer activity	IBA IEA	molecular_function
GO:0005525	GTP binding	IEA ISS	molecular_function
GO:0005737	Cytoplasm	IEA	cellular_component
GO:0005829	Cytosol	TAS	cellular_component
GO:0005834	Heterotrimeric G-protein complex	IBA	cellular_component
GO:0005886	Plasma membrane	TAS	cellular_component
GO:0007165	Signal transduction	NAS	biological_process
GO:0007188	Adenylate cyclase-modulating G-protein coupled receptor signaling pathway	IBA	biological_process
GO:0007601	Visual perception	TAS	biological_process
GO:0007603	Phototransduction, visible light	IMP TAS	biological_process
GO:0008283	Cell proliferation	IEA	biological_process
GO:0009416	Response to light stimulus	ISS	biological_process
GO:0009642	Response to light intensity	IEA	biological_process
GO:0016020	Membrane	NAS	cellular_component
GO:0016056	Rhodopsin mediated signaling pathway	IEA TAS	biological_process
GO:0016324	Apical plasma membrane	IEA	cellular_component
GO:0019003	GDP binding	ISS	molecular_function
GO:0019901	Protein kinase binding	ISS	molecular_function
GO:0022400	Regulation of rhodopsin mediated signaling pathway	TAS	biological_process
GO:0031234	Extrinsic component of cytoplasmic side of plasma membrane	IBA	cellular_component
GO:0031683	G-protein beta/gamma-subunit complex binding	IBA IEA	molecular_function
GO:0032391	Photoreceptor connecting cilium	IEA	cellular_component
GO:0042462	Eye photoreceptor cell development	IEA	biological_process
GO:0042622	Photoreceptor outer segment membrane	ISS	cellular_component
GO:0043025	Neuronal cell body	IEA	cellular_component
GO:0046872	Metal ion binding	IEA	molecular_function
GO:0050908	Detection of light stimulus involved in visual perception	IEA IMP	biological_process
GO:0050917	Sensory perception of umami taste	IBA IEA	biological_process
GO:0051343	Positive regulation of cyclic-nucleotide phosphodiesterase activity	IEA	biological_process
GO:0051344	Negative regulation of cyclic-nucleotide phosphodiesterase activity	ISS	biological_process
GO:0060041	Retina development in camera-type eye	IEA	biological_process
GO:0071257	Cellular response to electrical stimulus	IEA	biological_process
GO:0097381	Photoreceptor disc membrane	TAS	cellular_component

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4. Expression levels in datasets

Meta-analysis result

p-value up	p-value down	FDR up	FDR down
0.6774544280	0.8487095361	0.9999902473	1.0000000000

Individual experiment result
( "-" represent NA in the specific microarray platform )

Data source	Up or down	Log fold change
GSE11954	Down	-0.0716137703
GSE13712_SHEAR	Down	-0.0376841786
GSE13712_STATIC	Up	0.1673966824
GSE19018	Up	0.1363044824
GSE19899_A1	Down	-0.0046871614
GSE19899_A2	Down	-0.0141322700
PubMed_21979375_A1	Down	-0.0866247113
PubMed_21979375_A2	Down	-0.0918452311
GSE35957	Down	-0.0132001114
GSE36640	Up	0.0370516400
GSE54402	Down	-0.0907787298
GSE9593	Up	0.0079183954
GSE43922	Up	0.0215460641
GSE24585	Up	0.1590921697
GSE37065	Down	-0.0247242720
GSE28863_A1	Down	-0.0638183701
GSE28863_A2	Up	0.1348308210
GSE28863_A3	Up	0.1672003251
GSE28863_A4	Up	0.2287600686
GSE48662	Up	0.0644007601

5. Regulation relationships with compounds/drugs/microRNAs

Compounds

Not regulated by compounds

Drugs

Name	Drug	Accession number
Hydroxydimethylarsine Oxide	DB02994	EXPT00823
Guanosine-5'-Diphosphate	DB04315	EXPT01573
Tetrafluoroaluminate Ion	DB04444	EXPT00497

MicroRNAs

mirTarBase

No target information from mirTarBase

mirRecord

No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.

Navigator

1.General information
2.Neighbors in the network
3.Gene Ontology Annotation
4.Expression levels
5.Regulation
6.Text-mining results

HCSGD entry for GNAT1

1. General information

2. Neighbors in the network

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

4. Expression levels in datasets

Meta-analysis result

Individual experiment result ( "-" represent NA in the specific microarray platform )

( "-" represent NA in the specific microarray platform )

5. Regulation relationships with compounds/drugs/microRNAs

Compounds

Drugs

Name

Drug

Accession number

MicroRNAs

mirTarBase

mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.

Navigator

Individual experiment result
( "-" represent NA in the specific microarray platform )