HCSGD entry for GNAQ

1. General information

Official gene symbolGNAQ
Entrez ID2776
Gene full nameguanine nucleotide binding protein (G protein), q polypeptide
Other gene symbolsG-ALPHA-q GAQ
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentIEAbiological_process
GO:0001508Action potentialIBA IEAbiological_process
GO:0001664G-protein coupled receptor bindingIBA IEAmolecular_function
GO:0003924GTPase activityIEAmolecular_function
GO:0004871Signal transducer activityIBA IEAmolecular_function
GO:0005096GTPase activator activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005737CytoplasmTAScellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005834Heterotrimeric G-protein complexIBAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006469Negative regulation of protein kinase activityIMPbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007189Adenylate cyclase-activating G-protein coupled receptor signaling pathwayIBA IEAbiological_process
GO:0007202Activation of phospholipase C activityTASbiological_process
GO:0007215Glutamate receptor signaling pathwayIBA IEAbiological_process
GO:0007507Heart developmentIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016322Neuron remodelingIEAbiological_process
GO:0019001Guanyl nucleotide bindingIEAmolecular_function
GO:0021884Forebrain neuron developmentIEAbiological_process
GO:0030168Platelet activationTASbiological_process
GO:0031234Extrinsic component of cytoplasmic side of plasma membraneIBAcellular_component
GO:0031683G-protein beta/gamma-subunit complex bindingIBA IEAmolecular_function
GO:0031965Nuclear membraneIEAcellular_component
GO:0035412Regulation of catenin import into nucleusIMPbiological_process
GO:0042711Maternal behaviorIEAbiological_process
GO:0042733Embryonic digit morphogenesisIEAbiological_process
GO:0043547Positive regulation of GTPase activityIDAbiological_process
GO:0045634Regulation of melanocyte differentiationIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048066Developmental pigmentationIEAbiological_process
GO:0050821Protein stabilizationIMPbiological_process
GO:0060158Phospholipase C-activating dopamine receptor signaling pathwayIBA IEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78230696780.07563734280.99999024730.5192949426

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2527602641
GSE13712_SHEARDown-0.0139553129
GSE13712_STATICDown-0.0998140857
GSE19018Up0.1262133248
GSE19899_A1Down-0.6103036085
GSE19899_A2Down-0.7338427496
PubMed_21979375_A1Down-0.8160130869
PubMed_21979375_A2Down-0.8056166622
GSE35957Up0.5085994208
GSE36640Up0.3387727043
GSE54402Down-0.4543184363
GSE9593Up0.4826260162
GSE43922Down-0.5337622895
GSE24585Up0.1174289283
GSE37065Down-0.1521208726
GSE28863_A1Up0.0928110063
GSE28863_A2Up0.0602867142
GSE28863_A3Down-0.1243729299
GSE28863_A4Up0.0393873872
GSE48662Up0.2044203816

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-142-3pMIMAT0000434MIRT021640MicroarrayFunctional MTI (Weak)17612493
hsa-miR-128-3pMIMAT0000424MIRT021961MicroarrayFunctional MTI (Weak)17612493
hsa-miR-21-5pMIMAT0000076MIRT030765MicroarrayFunctional MTI (Weak)18591254
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.