HCSGD entry for GNAI3
1. General information
| Official gene symbol | GNAI3 |
|---|---|
| Entrez ID | 2773 |
| Gene full name | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 |
| Other gene symbols | 87U6 ARCND1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IBA | molecular_function |
| GO:0004871 | Signal transducer activity | IBA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005834 | Heterotrimeric G-protein complex | IBA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0006810 | Transport | NAS | biological_process |
| GO:0006906 | Vesicle fusion | IEA | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007193 | Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007194 | Negative regulation of adenylate cyclase activity | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0030496 | Midbody | IDA | cellular_component |
| GO:0031234 | Extrinsic component of cytoplasmic side of plasma membrane | IBA | cellular_component |
| GO:0031683 | G-protein beta/gamma-subunit complex binding | IBA | molecular_function |
| GO:0031821 | G-protein coupled serotonin receptor binding | IBA | molecular_function |
| GO:0032794 | GTPase activating protein binding | IEA | molecular_function |
| GO:0042588 | Zymogen granule | IEA | cellular_component |
| GO:0045121 | Membrane raft | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051301 | Cell division | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5961931917 | 0.2510293112 | 0.9999902473 | 0.9622278101 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1732402782 |
| GSE13712_SHEAR | Up | 0.1094432747 |
| GSE13712_STATIC | Up | 0.1259389994 |
| GSE19018 | Down | -0.0636629006 |
| GSE19899_A1 | Down | -0.0481095873 |
| GSE19899_A2 | Down | -0.0440573309 |
| PubMed_21979375_A1 | Up | 0.5719467334 |
| PubMed_21979375_A2 | Down | -0.1280020252 |
| GSE35957 | Down | -0.0521515350 |
| GSE36640 | Down | -0.5111174798 |
| GSE54402 | Up | 0.2989468235 |
| GSE9593 | Down | -0.0594190428 |
| GSE43922 | Down | -0.0475325207 |
| GSE24585 | Up | 0.0217398689 |
| GSE37065 | Up | 0.0277457379 |
| GSE28863_A1 | Up | 0.3711561735 |
| GSE28863_A2 | Up | 0.4637064596 |
| GSE28863_A3 | Down | -0.6229866365 |
| GSE28863_A4 | Down | -0.3944539826 |
| GSE48662 | Up | 0.0466954660 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002679 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-1 | MIMAT0000416 | MIRT023926 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025197 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
