HCSGD entry for GNA15

1. General information

Official gene symbolGNA15
Entrez ID2769
Gene full nameguanine nucleotide binding protein (G protein), alpha 15 (Gq class)
Other gene symbolsGNA16
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001664G-protein coupled receptor bindingIBAmolecular_function
GO:0003924GTPase activityIEAmolecular_function
GO:0004871Signal transducer activityIEA IGImolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005834Heterotrimeric G-protein complexIBA NAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayIBAbiological_process
GO:0007202Activation of phospholipase C activityTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIGIbiological_process
GO:0007207Phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathwayTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0019001Guanyl nucleotide bindingIEAmolecular_function
GO:0030168Platelet activationTASbiological_process
GO:0031234Extrinsic component of cytoplasmic side of plasma membraneIBAcellular_component
GO:0031683G-protein beta/gamma-subunit complex bindingIBA IEAmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
GO:0060158Phospholipase C-activating dopamine receptor signaling pathwayIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.76519849550.48967933210.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0009501539
GSE13712_SHEARDown-0.2116145290
GSE13712_STATICUp0.1072092689
GSE19018Down-0.1308978104
GSE19899_A1Down-0.0097042452
GSE19899_A2Down-0.0191659880
PubMed_21979375_A1Down-0.2391789610
PubMed_21979375_A2Down-0.0469045565
GSE35957Up0.0685001600
GSE36640Up0.0620604379
GSE54402Up0.1488883185
GSE9593Down-0.1488951022
GSE43922Up0.0558099773
GSE24585Up0.0683735105
GSE37065Up0.0400438099
GSE28863_A1Down-0.1489281490
GSE28863_A2Down-0.3534460267
GSE28863_A3Up0.3173213124
GSE28863_A4Down-0.0534301532
GSE48662Up0.2248323520

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.