HCSGD entry for GMPR


1. General information

Official gene symbolGMPR
Entrez ID2766
Gene full nameguanosine monophosphate reductase
Other gene symbolsGMPR1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003920GMP reductase activityIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0006144Purine nucleobase metabolic processTASbiological_process
GO:0009117Nucleotide metabolic processIEAbiological_process
GO:0009409Response to coldTASbiological_process
GO:0043101Purine-containing compound salvageTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0055086Nucleobase-containing small molecule metabolic processTASbiological_process
GO:1902560GMP reductase complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09231515140.12509647050.63821583510.6796004541

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3936654248
GSE13712_SHEARDown-0.3107643711
GSE13712_STATICUp0.1665891068
GSE19018Up0.0554649609
GSE19899_A1Down-0.3956993170
GSE19899_A2Up0.2294728044
PubMed_21979375_A1Down-1.4444117642
PubMed_21979375_A2Down-0.3064210138
GSE35957Down-0.9542031789
GSE36640Up1.1390213952
GSE54402Down-0.4556214217
GSE9593Up0.1831062672
GSE43922Down-0.8155079334
GSE24585Up0.6840912051
GSE37065Up1.1071486455
GSE28863_A1Down-0.1044053259
GSE28863_A2Up0.5739646466
GSE28863_A3Up0.0167862605
GSE28863_A4Up0.1703344643
GSE48662Down-0.1825153455

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Guanosine-5'-MonophosphateDB01972 EXPT00246

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.