HCSGD entry for EML4
1. General information
| Official gene symbol | EML4 |
|---|---|
| Entrez ID | 27436 |
| Gene full name | echinoderm microtubule associated protein like 4 |
| Other gene symbols | C2orf2 ELP120 EMAP-4 EMAPL4 ROPP120 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0007017 | Microtubule-based process | NAS | biological_process |
| GO:0007026 | Negative regulation of microtubule depolymerization | IEA | biological_process |
| GO:0007067 | Mitosis | NAS | biological_process |
| GO:0072686 | Mitotic spindle | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9988946317 | 0.0025391778 | 0.9999902473 | 0.0993071322 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3554141201 |
| GSE13712_SHEAR | Down | -0.1623976533 |
| GSE13712_STATIC | Down | -0.1896265855 |
| GSE19018 | Down | -0.4969741936 |
| GSE19899_A1 | Down | -0.3567656387 |
| GSE19899_A2 | Down | -0.8877429125 |
| PubMed_21979375_A1 | Down | -0.9667745278 |
| PubMed_21979375_A2 | Down | -0.7964443193 |
| GSE35957 | Down | -0.6574779870 |
| GSE36640 | Down | -0.7562390701 |
| GSE54402 | Down | -0.3707584213 |
| GSE9593 | Down | -0.6373161813 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.6221397994 |
| GSE28863_A2 | Down | -0.3293358444 |
| GSE28863_A3 | Down | -0.2815407167 |
| GSE28863_A4 | Down | -0.1190496189 |
| GSE48662 | Up | 0.1713713161 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT002765 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023446 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031894 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037042 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-652-3p | MIMAT0003322 | MIRT039520 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT043596 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
