HCSGD entry for MAT2B
1. General information
| Official gene symbol | MAT2B |
|---|---|
| Entrez ID | 27430 |
| Gene full name | methionine adenosyltransferase II, beta |
| Other gene symbols | MAT-II MATIIbeta Nbla02999 SDR23E1 TGR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000096 | Sulfur amino acid metabolic process | TAS | biological_process |
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005622 | Intracellular | IC | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006556 | S-adenosylmethionine biosynthetic process | IDA IEA | biological_process |
| GO:0006730 | One-carbon metabolic process | IEA | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0008831 | DTDP-4-dehydrorhamnose reductase activity | IEA | molecular_function |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0032259 | Methylation | TAS | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044237 | Cellular metabolic process | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045226 | Extracellular polysaccharide biosynthetic process | IEA | biological_process |
| GO:0048269 | Methionine adenosyltransferase complex | IDA | cellular_component |
| GO:0048270 | Methionine adenosyltransferase regulator activity | IDA | molecular_function |
| GO:0050662 | Coenzyme binding | IEA | molecular_function |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6964482694 | 0.1964147867 | 0.9999902473 | 0.8582061089 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1188457769 |
| GSE13712_SHEAR | Down | -0.0570177356 |
| GSE13712_STATIC | Up | 0.1168835197 |
| GSE19018 | Up | 0.0936463826 |
| GSE19899_A1 | Up | 0.2380448995 |
| GSE19899_A2 | Down | -0.6588734710 |
| PubMed_21979375_A1 | Down | -0.3001445547 |
| PubMed_21979375_A2 | Down | -0.8487986291 |
| GSE35957 | Down | -0.1299680532 |
| GSE36640 | Down | -0.7822721734 |
| GSE54402 | Down | -0.0588219064 |
| GSE9593 | Down | -0.0147393155 |
| GSE43922 | Up | 0.0088407992 |
| GSE24585 | Down | -0.0734292813 |
| GSE37065 | Up | 0.0783023403 |
| GSE28863_A1 | Up | 0.5262009430 |
| GSE28863_A2 | Up | 0.2480343671 |
| GSE28863_A3 | Up | 0.0747784556 |
| GSE28863_A4 | Down | -0.1003713394 |
| GSE48662 | Down | -0.3487522117 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019945 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020796 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029818 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032407 | Proteomics | Functional MTI (Weak) | 18668040 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
