HCSGD entry for SGSM3


1. General information

Official gene symbolSGSM3
Entrez ID27352
Gene full namesmall G protein signaling modulator 3
Other gene symbolsMAP RABGAP5 RUSC3 RUTBC3 RabGAP-5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005097Rab GTPase activator activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005921Gap junctionIEAcellular_component
GO:0007050Cell cycle arrestIEAbiological_process
GO:0017137Rab GTPase bindingIDAmolecular_function
GO:0032483Regulation of Rab protein signal transductionIEPbiological_process
GO:0032486Rap protein signal transductionIEPbiological_process
GO:0045732Positive regulation of protein catabolic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.28128395580.89117963600.97868197441.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0128484833
GSE13712_SHEARDown-0.4020476342
GSE13712_STATICDown-0.0311044349
GSE19018Up0.2206981638
GSE19899_A1Down-0.0554015487
GSE19899_A2Up0.3719915998
PubMed_21979375_A1Up0.6254020122
PubMed_21979375_A2Up0.5390172664
GSE35957Down-0.0410062186
GSE36640Up0.2583868537
GSE54402Up0.0869061055
GSE9593Up0.0009927697
GSE43922Up0.0545392555
GSE24585Up0.2412546676
GSE37065Down-0.1160702993
GSE28863_A1Down-0.0442533078
GSE28863_A2Down-0.0433489826
GSE28863_A3Down-0.1727845017
GSE28863_A4Down-0.0084023694
GSE48662Up0.3972677685

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022600MicroarrayFunctional MTI (Weak)18668037
hsa-let-7e-5pMIMAT0000066MIRT051662CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.