HCSGD entry for APOBEC3C
1. General information
| Official gene symbol | APOBEC3C |
|---|---|
| Entrez ID | 27350 |
| Gene full name | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| Other gene symbols | A3C APOBEC1L ARDC2 ARDC4 ARP5 PBI bK150C2.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0009972 | Cytidine deamination | IDA | biological_process |
| GO:0010529 | Negative regulation of transposition | IDA | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016814 | Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines | IEA | molecular_function |
| GO:0045071 | Negative regulation of viral genome replication | IDA | biological_process |
| GO:0045087 | Innate immune response | IEA | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0080111 | DNA demethylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0961215797 | 0.1849898446 | 0.6489576154 | 0.8337530308 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5170802281 |
| GSE13712_SHEAR | Up | 0.1899393892 |
| GSE13712_STATIC | Up | 0.6430664408 |
| GSE19018 | Up | 0.0608437695 |
| GSE19899_A1 | Up | 0.0594792632 |
| GSE19899_A2 | Up | 0.7836709500 |
| PubMed_21979375_A1 | Up | 0.1681392573 |
| PubMed_21979375_A2 | Down | -0.0397315612 |
| GSE35957 | Down | -0.4692811994 |
| GSE36640 | Up | 0.2187505364 |
| GSE54402 | Down | -0.4684597932 |
| GSE9593 | Up | 0.4420019560 |
| GSE43922 | Down | -0.0204483033 |
| GSE24585 | Up | 0.2060938856 |
| GSE37065 | Up | 0.1244643536 |
| GSE28863_A1 | Down | -0.4949368072 |
| GSE28863_A2 | Down | -0.4899998242 |
| GSE28863_A3 | Down | -0.9274569336 |
| GSE28863_A4 | Up | 0.0242901611 |
| GSE48662 | Up | 0.7117317766 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049344 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
