HCSGD entry for KCNMB4
1. General information
| Official gene symbol | KCNMB4 |
|---|---|
| Entrez ID | 27345 |
| Gene full name | potassium large conductance calcium-activated channel, subfamily M, beta member 4 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001508 | Action potential | IDA | biological_process |
| GO:0005513 | Detection of calcium ion | IDA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IDA | cellular_component |
| GO:0006813 | Potassium ion transport | IDA | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008076 | Voltage-gated potassium channel complex | IDA | cellular_component |
| GO:0015269 | Calcium-activated potassium channel activity | IDA IEA | molecular_function |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0019228 | Neuronal action potential | IDA | biological_process |
| GO:0019229 | Regulation of vasoconstriction | TAS | biological_process |
| GO:0034220 | Ion transmembrane transport | IDA | biological_process |
| GO:0046928 | Regulation of neurotransmitter secretion | TAS | biological_process |
| GO:0055085 | Transmembrane transport | IDA | biological_process |
| GO:0071805 | Potassium ion transmembrane transport | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4549091220 | 0.3292526006 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0085235582 |
| GSE13712_SHEAR | Down | -0.3815431371 |
| GSE13712_STATIC | Down | -0.4125106298 |
| GSE19018 | Down | -0.1625940685 |
| GSE19899_A1 | Up | 0.2252344352 |
| GSE19899_A2 | Up | 0.1738787503 |
| PubMed_21979375_A1 | Up | 0.1146863611 |
| PubMed_21979375_A2 | Down | -0.0577996203 |
| GSE35957 | Up | 0.1332005220 |
| GSE36640 | Up | 0.4157561245 |
| GSE54402 | Down | -0.2883305908 |
| GSE9593 | Up | 0.0645930319 |
| GSE43922 | Up | 0.3212736161 |
| GSE24585 | Up | 0.3100210513 |
| GSE37065 | Up | 0.0067638364 |
| GSE28863_A1 | Down | -0.5451992280 |
| GSE28863_A2 | Up | 0.0135597670 |
| GSE28863_A3 | Down | -0.0824453915 |
| GSE28863_A4 | Down | -0.1336943956 |
| GSE48662 | Up | 0.3827063269 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Miconazole | DB01110 | APRD01115 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024739 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026374 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
