HCSGD entry for RABGEF1
1. General information
| Official gene symbol | RABGEF1 |
|---|---|
| Entrez ID | 27342 |
| Gene full name | RAB guanine nucleotide exchange factor (GEF) 1 |
| Other gene symbols | RABEX5 rabex-5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005769 | Early endosome | IEA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0032313 | Regulation of Rab GTPase activity | IDA | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0055037 | Recycling endosome | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6314299723 | 0.5259205463 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1352916789 |
| GSE13712_SHEAR | Down | -0.0307214331 |
| GSE13712_STATIC | Up | 0.3986533234 |
| GSE19018 | Up | 0.0289474767 |
| GSE19899_A1 | Down | -0.0072698653 |
| GSE19899_A2 | Up | 0.6400756288 |
| PubMed_21979375_A1 | Up | 0.2858100979 |
| PubMed_21979375_A2 | Down | -0.2579582416 |
| GSE35957 | Down | -0.3871111041 |
| GSE36640 | Down | -0.1802691770 |
| GSE54402 | Up | 0.2488920768 |
| GSE9593 | Up | 0.0600034897 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.1077020238 |
| GSE28863_A2 | Down | -0.0054537379 |
| GSE28863_A3 | Down | -0.0609451598 |
| GSE28863_A4 | Down | -0.1114670703 |
| GSE48662 | Up | 0.1083945637 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023256 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
