HCSGD entry for TNRC6A
1. General information
| Official gene symbol | TNRC6A |
|---|---|
| Entrez ID | 27327 |
| Gene full name | trinucleotide repeat containing 6A |
| Other gene symbols | CAGH26 GW1 GW182 TNRC6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000932 | Cytoplasmic mRNA processing body | IDA | cellular_component |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0007219 | Notch signaling pathway | TAS | biological_process |
| GO:0008543 | Fibroblast growth factor receptor signaling pathway | TAS | biological_process |
| GO:0009267 | Cellular response to starvation | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0031047 | Gene silencing by RNA | IEA | biological_process |
| GO:0035068 | Micro-ribonucleoprotein complex | IDA | cellular_component |
| GO:0035278 | Negative regulation of translation involved in gene silencing by miRNA | IDA | biological_process |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0048015 | Phosphatidylinositol-mediated signaling | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8540356293 | 0.1868483188 | 0.9999902473 | 0.8381605658 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1956868645 |
| GSE13712_SHEAR | Up | 0.2480071247 |
| GSE13712_STATIC | Down | -0.0427980181 |
| GSE19018 | Down | -0.1065468137 |
| GSE19899_A1 | Down | -0.1671641240 |
| GSE19899_A2 | Up | 0.0368883698 |
| PubMed_21979375_A1 | Down | -0.2788214732 |
| PubMed_21979375_A2 | Up | 0.1635580427 |
| GSE35957 | Down | -0.1448050068 |
| GSE36640 | Down | -0.2874080845 |
| GSE54402 | Down | -0.0874696192 |
| GSE9593 | Down | -0.1946474353 |
| GSE43922 | Down | -0.0082096313 |
| GSE24585 | Down | -0.1906025759 |
| GSE37065 | Down | -0.0127528785 |
| GSE28863_A1 | Up | 0.5867467853 |
| GSE28863_A2 | Up | 0.2477430715 |
| GSE28863_A3 | Down | -0.3092637889 |
| GSE28863_A4 | Up | 0.1783215509 |
| GSE48662 | Down | -0.5199682540 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT004785 | Luciferase reporter assay | Functional MTI | 19767416 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT020089 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT026015 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032154 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-484 | MIMAT0002174 | MIRT041866 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044774 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047876 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050426 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
