HCSGD entry for TOX3
1. General information
| Official gene symbol | TOX3 |
|---|---|
| Entrez ID | 27324 |
| Gene full name | TOX high mobility group box family member 3 |
| Other gene symbols | CAGF9 TNRC9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003682 | Chromatin binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0034056 | Estrogen response element binding | IDA | molecular_function |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0043524 | Negative regulation of neuron apoptotic process | IDA | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0051219 | Phosphoprotein binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8498281334 | 0.5378297139 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0880520824 |
| GSE13712_SHEAR | Down | -0.1441440944 |
| GSE13712_STATIC | Down | -0.0708001851 |
| GSE19018 | Up | 0.0400095271 |
| GSE19899_A1 | Up | 0.1254514457 |
| GSE19899_A2 | Down | -0.0370982259 |
| PubMed_21979375_A1 | Up | 0.0515153234 |
| PubMed_21979375_A2 | Up | 0.0842787619 |
| GSE35957 | Up | 0.1819949476 |
| GSE36640 | Down | -0.1242459840 |
| GSE54402 | Up | 0.0553485436 |
| GSE9593 | Up | 0.0272297372 |
| GSE43922 | Up | 0.0226337787 |
| GSE24585 | Down | -0.7979585039 |
| GSE37065 | Down | -0.0010746171 |
| GSE28863_A1 | Up | 0.0053978646 |
| GSE28863_A2 | Up | 0.0051865418 |
| GSE28863_A3 | Up | 0.0083280444 |
| GSE28863_A4 | Down | -0.0229269934 |
| GSE48662 | Up | 0.0437665345 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-149-5p | MIMAT0000450 | MIRT045405 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052048 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
