HCSGD entry for BHLHE22
1. General information
| Official gene symbol | BHLHE22 |
|---|---|
| Entrez ID | 27319 |
| Gene full name | basic helix-loop-helix family, member e22 |
| Other gene symbols | BHLHB5 Beta3 CAGL85 TNRC20 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000981 | Sequence-specific DNA binding RNA polymerase II transcription factor activity | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0021540 | Corpus callosum morphogenesis | IEA | biological_process |
| GO:0021796 | Cerebral cortex regionalization | IEA | biological_process |
| GO:0021957 | Corticospinal tract morphogenesis | IEA | biological_process |
| GO:0021960 | Anterior commissure morphogenesis | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0060040 | Retinal bipolar neuron differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4796765586 | 0.9079344858 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0100275398 |
| GSE13712_SHEAR | Down | -0.2341388992 |
| GSE13712_STATIC | Down | -0.1144863383 |
| GSE19018 | Up | 0.1197965304 |
| GSE19899_A1 | Up | 0.1634110120 |
| GSE19899_A2 | Up | 0.2972938364 |
| PubMed_21979375_A1 | Down | -0.3172993831 |
| PubMed_21979375_A2 | Down | -0.0397275667 |
| GSE35957 | Up | 0.1130955441 |
| GSE36640 | Down | -0.0730197753 |
| GSE54402 | Up | 0.0634159658 |
| GSE9593 | Up | 0.0142454229 |
| GSE43922 | Up | 0.0971256151 |
| GSE24585 | Up | 0.0186636226 |
| GSE37065 | Up | 0.0513404356 |
| GSE28863_A1 | Down | -0.0533428809 |
| GSE28863_A2 | Up | 0.2743531764 |
| GSE28863_A3 | Up | 0.2772294635 |
| GSE28863_A4 | Up | 0.0876677305 |
| GSE48662 | Up | 0.0338218647 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017669 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
