HCSGD entry for GLDC
1. General information
| Official gene symbol | GLDC |
|---|---|
| Entrez ID | 2731 |
| Gene full name | glycine dehydrogenase (decarboxylating) |
| Other gene symbols | GCE GCSP HYGN1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004375 | Glycine dehydrogenase (decarboxylating) activity | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006546 | Glycine catabolic process | IEA | biological_process |
| GO:0009055 | Electron carrier activity | TAS | molecular_function |
| GO:0016829 | Lyase activity | IEA | molecular_function |
| GO:0030170 | Pyridoxal phosphate binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0016752289 | 0.9852490141 | 0.1094376238 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.9135051748 |
| GSE13712_SHEAR | Up | 1.8542662487 |
| GSE13712_STATIC | Up | 1.3490087074 |
| GSE19018 | Up | 0.2805274198 |
| GSE19899_A1 | Up | 0.4859635470 |
| GSE19899_A2 | Up | 1.6615477226 |
| PubMed_21979375_A1 | Up | 0.7173043280 |
| PubMed_21979375_A2 | Up | 2.3773812978 |
| GSE35957 | Up | 0.0582701800 |
| GSE36640 | Down | -0.1250335020 |
| GSE54402 | Up | 1.1661434398 |
| GSE9593 | Up | 0.5942548867 |
| GSE43922 | Up | 0.0502166692 |
| GSE24585 | Up | 0.0169565882 |
| GSE37065 | Down | -0.0169843032 |
| GSE28863_A1 | Down | -0.0441354592 |
| GSE28863_A2 | Up | 0.0625324073 |
| GSE28863_A3 | Up | 0.2188971475 |
| GSE28863_A4 | Down | -0.0628200261 |
| GSE48662 | Down | -0.1845902665 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glycine | DB00145 | NUTR00028 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-423-3p | MIMAT0001340 | MIRT042509 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
