HCSGD entry for LSM3
1. General information
| Official gene symbol | LSM3 |
|---|---|
| Entrez ID | 27258 |
| Gene full name | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| Other gene symbols | SMX4 USS2 YLR438C |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000288 | Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | TAS | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IC | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006397 | MRNA processing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0043928 | Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | TAS | biological_process |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9909354090 | 0.0126595988 | 0.9999902473 | 0.2222903936 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1060488636 |
| GSE13712_SHEAR | Down | -0.0491754596 |
| GSE13712_STATIC | Down | -0.2542611638 |
| GSE19018 | Down | -0.2413598779 |
| GSE19899_A1 | Down | -0.3607641179 |
| GSE19899_A2 | Down | -0.8106965842 |
| PubMed_21979375_A1 | Down | -0.4550337079 |
| PubMed_21979375_A2 | Down | -0.4143426124 |
| GSE35957 | Down | -0.1359168882 |
| GSE36640 | Down | -0.6932393653 |
| GSE54402 | Down | -0.3209464866 |
| GSE9593 | Down | -0.0279418083 |
| GSE43922 | Down | -0.5562637880 |
| GSE24585 | Down | -0.1625101246 |
| GSE37065 | Down | -0.2587136608 |
| GSE28863_A1 | Down | -0.3842651996 |
| GSE28863_A2 | Down | -0.4127994456 |
| GSE28863_A3 | Down | -0.0536593466 |
| GSE28863_A4 | Up | 0.1992324393 |
| GSE48662 | Down | -0.2134901281 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT021014 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030252 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT045864 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048272 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
