HCSGD entry for COQ2
1. General information
| Official gene symbol | COQ2 |
|---|---|
| Entrez ID | 27235 |
| Gene full name | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase |
| Other gene symbols | CL640 COQ10D1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002083 | 4-hydroxybenzoate decaprenyltransferase activity | IEA | molecular_function |
| GO:0004659 | Prenyltransferase activity | IEA | molecular_function |
| GO:0005739 | Mitochondrion | RCA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0006071 | Glycerol metabolic process | IGI | biological_process |
| GO:0006744 | Ubiquinone biosynthetic process | IDA IEA TAS | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0008299 | Isoprenoid biosynthetic process | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA RCA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0047293 | 4-hydroxybenzoate nonaprenyltransferase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9813623495 | 0.0237309373 | 0.9999902473 | 0.2974390476 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0232238917 |
| GSE13712_SHEAR | Up | 0.1304867571 |
| GSE13712_STATIC | Down | -0.0831697367 |
| GSE19018 | Down | -0.6947447477 |
| GSE19899_A1 | Down | -0.0970559555 |
| GSE19899_A2 | Down | -0.1965297338 |
| PubMed_21979375_A1 | Up | 0.3543265255 |
| PubMed_21979375_A2 | Down | -0.0067661828 |
| GSE35957 | Down | -0.8966508669 |
| GSE36640 | Down | -0.8992045436 |
| GSE54402 | Up | 0.0888814862 |
| GSE9593 | Down | -0.5830305456 |
| GSE43922 | Down | -0.0701092458 |
| GSE24585 | Down | -0.0503425957 |
| GSE37065 | Down | -0.0143085033 |
| GSE28863_A1 | Down | -0.1051758567 |
| GSE28863_A2 | Down | -0.2546058214 |
| GSE28863_A3 | Down | -0.5442022931 |
| GSE28863_A4 | Up | 0.0584233117 |
| GSE48662 | Down | -0.7951895719 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-99a-5p | MIMAT0000097 | MIRT027397 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT027979 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028814 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
