HCSGD entry for NMRK2
1. General information
| Official gene symbol | NMRK2 |
|---|---|
| Entrez ID | 27231 |
| Gene full name | nicotinamide riboside kinase 2 |
| Other gene symbols | ITGB1BP3 MIBP NRK2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0009435 | NAD biosynthetic process | IEA | biological_process |
| GO:0019359 | Nicotinamide nucleotide biosynthetic process | IEA | biological_process |
| GO:0045662 | Negative regulation of myoblast differentiation | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0050262 | Ribosylnicotinamide kinase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2139487557 | 0.8865094297 | 0.8910356329 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0745033371 |
| GSE13712_SHEAR | Down | -0.0071598430 |
| GSE13712_STATIC | Down | -0.1466181526 |
| GSE19018 | Down | -0.0617249791 |
| GSE19899_A1 | Down | -0.1169094524 |
| GSE19899_A2 | Up | 0.1487760996 |
| PubMed_21979375_A1 | Down | -0.1146901558 |
| PubMed_21979375_A2 | Down | -0.0254848774 |
| GSE35957 | Up | 0.1069434406 |
| GSE36640 | Up | 0.0789773344 |
| GSE54402 | Up | 0.0442164472 |
| GSE9593 | Up | 0.0896946679 |
| GSE43922 | Up | 0.0503291428 |
| GSE24585 | Up | 1.4216310299 |
| GSE37065 | Down | -0.0993192643 |
| GSE28863_A1 | Down | -0.0633741844 |
| GSE28863_A2 | Up | 0.0404306768 |
| GSE28863_A3 | Up | 0.4352253120 |
| GSE28863_A4 | Up | 0.1148492908 |
| GSE48662 | Down | -0.0308301670 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025069 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028997 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
