HCSGD entry for SIGLEC8
1. General information
| Official gene symbol | SIGLEC8 |
|---|---|
| Entrez ID | 27181 |
| Gene full name | sialic acid binding Ig-like lectin 8 |
| Other gene symbols | SAF2 SIGLEC-8 SIGLEC8L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004888 | Transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030246 | Carbohydrate binding | TAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6765730937 | 0.6233921052 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0227851868 |
| GSE13712_SHEAR | Up | 0.0756333390 |
| GSE13712_STATIC | Down | -0.0814949664 |
| GSE19018 | Up | 0.0303939133 |
| GSE19899_A1 | Down | -0.0222189464 |
| GSE19899_A2 | Up | 0.0250263151 |
| PubMed_21979375_A1 | Down | -0.0135493604 |
| PubMed_21979375_A2 | Down | -0.2064523096 |
| GSE35957 | Down | -0.0707709647 |
| GSE36640 | Down | -0.0268149026 |
| GSE54402 | Down | -0.0166033300 |
| GSE9593 | Up | 0.0957643348 |
| GSE43922 | Up | 0.0293600086 |
| GSE24585 | Up | 0.1363840045 |
| GSE37065 | Up | 0.0397699873 |
| GSE28863_A1 | Down | -0.2866398621 |
| GSE28863_A2 | Down | -0.2942252619 |
| GSE28863_A3 | Up | 0.6545658041 |
| GSE28863_A4 | Up | 0.0269463270 |
| GSE48662 | Up | 0.0102708442 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017964 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
