HCSGD entry for DENND2A


1. General information

Official gene symbolDENND2A
Entrez ID27147
Gene full nameDENN/MADD domain containing 2A
Other gene symbolsFAM31D KIAA1277
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005737CytoplasmIEAcellular_component
GO:0015031Protein transportIEAbiological_process
GO:0015629Actin cytoskeletonIDAcellular_component
GO:0017112Rab guanyl-nucleotide exchange factor activityIDAmolecular_function
GO:0032313Regulation of Rab GTPase activityIDAbiological_process
GO:0032318Regulation of Ras GTPase activityIDAbiological_process
GO:0042147Retrograde transport, endosome to GolgiIMPbiological_process
GO:0043087Regulation of GTPase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23950958550.07602204320.92540267140.5206807702

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0132965196
GSE13712_SHEARDown-0.1070685016
GSE13712_STATICUp0.0034476986
GSE19018Up0.2558138502
GSE19899_A1Down-0.7868705658
GSE19899_A2Down-1.9660484903
PubMed_21979375_A1Down-1.1510994473
PubMed_21979375_A2Down-0.4237381638
GSE35957Down-0.1191755682
GSE36640Down-0.0847173189
GSE54402Down-0.9793079069
GSE9593Up0.1069391463
GSE43922Down-0.2278829112
GSE24585Up0.3414137018
GSE37065Down-0.1195769811
GSE28863_A1Up1.1646442188
GSE28863_A2Up0.9809238870
GSE28863_A3Up0.3641204594
GSE28863_A4Up0.1164046059
GSE48662Up0.0871681398

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-185-5pMIMAT0000455MIRT045332CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.