HCSGD entry for KCNH5

1. General information

Official gene symbolKCNH5
Entrez ID27133
Gene full namepotassium voltage-gated channel, subfamily H (eag-related), member 5
Other gene symbolsEAG2 H-EAG2 Kv10.2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000155Phosphorelay sensor kinase activityIEAmolecular_function
GO:0005249Voltage-gated potassium channel activityIBA IEAmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005622IntracellularIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIBAcellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0009986Cell surfaceIDAcellular_component
GO:0010389Regulation of G2/M transition of mitotic cell cycleIDAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0042391Regulation of membrane potentialIBAbiological_process
GO:0071805Potassium ion transmembrane transportIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84769590440.77151804260.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0823587753
GSE13712_SHEARUp0.0908573334
GSE13712_STATICDown-0.0084129379
GSE19018Down-0.0395619307
GSE19899_A1Down-0.0160238317
GSE19899_A2Up0.0701728118
PubMed_21979375_A1Down-0.0996839154
PubMed_21979375_A2Up0.1437893075
GSE35957Up0.0950805415
GSE36640Down-0.0126413349
GSE54402Down-0.0470265447
GSE9593Up0.0317699506
GSE43922Up0.0087191115
GSE24585Up0.0805737896
GSE37065Up0.0248236106
GSE28863_A1Down-0.2618372436
GSE28863_A2Down-0.1243507880
GSE28863_A3Up0.1846753243
GSE28863_A4Up0.0370891369
GSE48662Down-0.0768048487

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.