HCSGD entry for INPP5J
1. General information
| Official gene symbol | INPP5J |
|---|---|
| Entrez ID | 27124 |
| Gene full name | inositol polyphosphate-5-phosphatase J |
| Other gene symbols | INPP5 PIB5PA PIPP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001726 | Ruffle | IDA IEA | cellular_component |
| GO:0004445 | Inositol-polyphosphate 5-phosphatase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0010977 | Negative regulation of neuron projection development | IEA | biological_process |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
| GO:0030426 | Growth cone | IEA | cellular_component |
| GO:0031115 | Negative regulation of microtubule polymerization | IEA | biological_process |
| GO:0033137 | Negative regulation of peptidyl-serine phosphorylation | IEA | biological_process |
| GO:0034485 | Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity | IEA | molecular_function |
| GO:0043198 | Dendritic shaft | IEA | cellular_component |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046856 | Phosphatidylinositol dephosphorylation | IEA | biological_process |
| GO:0052658 | Inositol-1,4,5-trisphosphate 5-phosphatase activity | IEA | molecular_function |
| GO:0052659 | Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6521195965 | 0.7497314768 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1392922577 |
| GSE13712_SHEAR | Up | 0.0019468386 |
| GSE13712_STATIC | Up | 0.1267881342 |
| GSE19018 | Up | 0.0764248385 |
| GSE19899_A1 | Up | 0.1023467741 |
| GSE19899_A2 | Down | -0.2158124179 |
| PubMed_21979375_A1 | Up | 0.0242956211 |
| PubMed_21979375_A2 | Down | -0.0935282022 |
| GSE35957 | Up | 0.0745247836 |
| GSE36640 | Down | -0.0476150521 |
| GSE54402 | Up | 0.0537362504 |
| GSE9593 | Up | 0.0418573862 |
| GSE43922 | Up | 0.0241302736 |
| GSE24585 | Up | 0.1601879645 |
| GSE37065 | Up | 0.0016397323 |
| GSE28863_A1 | Down | -0.1055350134 |
| GSE28863_A2 | Down | -0.1331387523 |
| GSE28863_A3 | Up | 0.4345374780 |
| GSE28863_A4 | Up | 0.0275060487 |
| GSE48662 | Down | -0.0132600792 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-346 | MIMAT0000773 | MIRT004238 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030023 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
