HCSGD entry for PDE7B
1. General information
| Official gene symbol | PDE7B |
|---|---|
| Entrez ID | 27115 |
| Gene full name | phosphodiesterase 7B |
| Other gene symbols | bA472E5.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity | IEA | molecular_function |
| GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006198 | CAMP catabolic process | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4595699745 | 0.0014246571 | 0.9999902473 | 0.0729512621 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0576711976 |
| GSE13712_SHEAR | Down | -0.2601634704 |
| GSE13712_STATIC | Up | 0.0033298885 |
| GSE19018 | Up | 0.6114478853 |
| GSE19899_A1 | Down | -0.9421555112 |
| GSE19899_A2 | Down | -2.6997596304 |
| PubMed_21979375_A1 | Down | -1.7722620655 |
| PubMed_21979375_A2 | Down | -1.0295444295 |
| GSE35957 | Up | 0.1218252606 |
| GSE36640 | Down | -2.4594895311 |
| GSE54402 | Down | -1.6571350939 |
| GSE9593 | Up | 0.1003017435 |
| GSE43922 | Down | -2.3773694209 |
| GSE24585 | Up | 0.2535856565 |
| GSE37065 | Down | -0.1112436621 |
| GSE28863_A1 | Up | 0.2900981156 |
| GSE28863_A2 | Up | 1.0901534676 |
| GSE28863_A3 | Up | 0.0266889085 |
| GSE28863_A4 | Down | -0.4382692630 |
| GSE48662 | Down | -0.4257695036 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Ketotifen | DB00920 | APRD01061 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
