HCSGD entry for FOXP1

1. General information

Official gene symbolFOXP1
Entrez ID27086
Gene full nameforkhead box P1
Other gene symbols12CC4 QRF1 hFKH1B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001701In utero embryonic developmentIEAbiological_process
GO:0002053Positive regulation of mesenchymal cell proliferationIBA IEAbiological_process
GO:0002329Pre-B cell differentiationIBA IEAbiological_process
GO:0002639Positive regulation of immunoglobulin productionIBA IEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003682Chromatin bindingIBA IEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIBAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007389Pattern specification processIBAbiological_process
GO:0007519Skeletal muscle tissue developmentIBA IEAbiological_process
GO:0008045Motor neuron axon guidanceIEAbiological_process
GO:0008301DNA binding, bendingIBAmolecular_function
GO:0009790Embryo developmentIBAbiological_process
GO:0021517Ventral spinal cord developmentIEAbiological_process
GO:0030324Lung developmentIBAbiological_process
GO:0033152Immunoglobulin V(D)J recombinationIBA IEAbiological_process
GO:0042803Protein homodimerization activityIBA IEAmolecular_function
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045214Sarcomere organizationIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDA IEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0046982Protein heterodimerization activityIBA IEAmolecular_function
GO:0048745Smooth muscle tissue developmentIBA IEAbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIBA IEAbiological_process
GO:0055007Cardiac muscle cell differentiationIBA IEAbiological_process
GO:0060043Regulation of cardiac muscle cell proliferationIEAbiological_process
GO:0061140Lung secretory cell differentiationIEAbiological_process
GO:1901250Negative regulation of lung goblet cell differentiationIEAbiological_process
GO:2000727Positive regulation of cardiac muscle cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98903568630.01130831660.99999024730.2102021186

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5299462864
GSE13712_SHEARDown-0.9668093000
GSE13712_STATICDown-0.2762247096
GSE19018Down-0.4178359446
GSE19899_A1Down-0.3649849296
GSE19899_A2Down-0.0557941407
PubMed_21979375_A1Down-0.7463314665
PubMed_21979375_A2Down-0.5445572869
GSE35957Down-0.2262053610
GSE36640Down-0.8483070587
GSE54402Up0.0699425847
GSE9593Down-0.3898872833
GSE43922Down-0.1473887207
GSE24585Up0.1362088505
GSE37065Down-0.0399763160
GSE28863_A1Up0.2941076489
GSE28863_A2Down-0.1003912645
GSE28863_A3Down-0.1543783419
GSE28863_A4Down-0.3117724412
GSE48662Up0.1640291235

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT001054qRT-PCR//Western blot//Luciferase reporter assayFunctional MTI18818206
hsa-miR-1MIMAT0000416MIRT001054Luciferase reporter assay//Western blotFunctional MTI18593903
hsa-miR-122-5pMIMAT0000421MIRT003088Luciferase reporter assay//qRT-PCRFunctional MTI19296470
hsa-miR-34a-5pMIMAT0000255MIRT005546Flow//Immunoblot//Luciferase reporter assay//Reporter assay;Western blot;OtherFunctional MTI20598588
hsa-miR-34a-5pMIMAT0000255MIRT005546Luciferase reporter assay//Western blotFunctional MTI21460242
hsa-miR-335-5pMIMAT0000765MIRT018196MicroarrayFunctional MTI (Weak)18185580
hsa-miR-33a-5pMIMAT0000091MIRT028242SequencingFunctional MTI (Weak)20371350
hsa-miR-22-3pMIMAT0000077MIRT030641SequencingFunctional MTI (Weak)20371350
hsa-miR-1229-3pMIMAT0005584MIRT036350CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044777CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048404CLASHFunctional MTI (Weak)23622248
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-1MIMAT0000416NAhsa-miR-1{Western blot}{overexpression by miRNA precursor transfection}18818206
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.