HCSGD entry for ATP2C1

1. General information

Official gene symbolATP2C1
Entrez ID27032
Gene full nameATPase, Ca++ transporting, type 2C, member 1
Other gene symbolsATP2C1A BCPM HHD PMR1 SPCA1 hSPCA1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIDA TAScellular_component
GO:0004871Signal transducer activityIMPmolecular_function
GO:0005388Calcium-transporting ATPase activityIDA IEA IMPmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005794Golgi apparatusIDAcellular_component
GO:0005802Trans-Golgi networkIDAcellular_component
GO:0006200ATP catabolic processIDA IMPbiological_process
GO:0006816Calcium ion transportIDA IMPbiological_process
GO:0006828Manganese ion transportIDAbiological_process
GO:0006874Cellular calcium ion homeostasisIDA IMPbiological_process
GO:0007165Signal transductionIMPbiological_process
GO:0008152Metabolic processIDA IMPbiological_process
GO:0008544Epidermis developmentIMPbiological_process
GO:0015410Manganese-transporting ATPase activityIDAmolecular_function
GO:0016021Integral component of membraneIEA NAScellular_component
GO:0016339Calcium-dependent cell-cell adhesionIMPbiological_process
GO:0019829Cation-transporting ATPase activityIEAmolecular_function
GO:0030026Cellular manganese ion homeostasisIDAbiological_process
GO:0030145Manganese ion bindingIDAmolecular_function
GO:0031532Actin cytoskeleton reorganizationIMPbiological_process
GO:0032468Golgi calcium ion homeostasisIMPbiological_process
GO:0032472Golgi calcium ion transportIMPbiological_process
GO:0034220Ion transmembrane transportIDA TASbiological_process
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIMPbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0055085Transmembrane transportIDA TASbiological_process
GO:0070588Calcium ion transmembrane transportIDA IMPbiological_process
GO:0071421Manganese ion transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.19511093800.51190730220.85591916671.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2887022299
GSE13712_SHEARDown-0.0206111648
GSE13712_STATICUp0.2499649823
GSE19018Up0.2583141635
GSE19899_A1Up0.1420952031
GSE19899_A2Up0.2845450851
PubMed_21979375_A1Up0.3005535665
PubMed_21979375_A2Up0.0907051502
GSE35957Up0.2873235431
GSE36640Up0.8573961306
GSE54402Down-0.0289734668
GSE9593Up0.3262537733
GSE43922Up0.0527521390
GSE24585Down-0.0065432335
GSE37065Down-0.0385446801
GSE28863_A1Up0.1214788222
GSE28863_A2Up0.3992277149
GSE28863_A3Down-0.6745635552
GSE28863_A4Down-0.3604037101
GSE48662Down-0.4482915066

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

EnfluraneDB00228 APRD00234
IsofluraneDB00753 APRD00212
MethoxyfluraneDB01028 APRD00744
DesfluraneDB01189 APRD00907
SevofluraneDB01236 APRD00219
CalciumDB01373 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-18a-3pMIMAT0002891MIRT040808CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.