HCSGD entry for NPTN
1. General information
| Official gene symbol | NPTN |
|---|---|
| Entrez ID | 27020 |
| Gene full name | neuroplastin |
| Other gene symbols | GP55 GP65 SDFR1 SDR1 np55 np65 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001934 | Positive regulation of protein phosphorylation | ISS | biological_process |
| GO:0005105 | Type 1 fibroblast growth factor receptor binding | ISS | molecular_function |
| GO:0007156 | Homophilic cell adhesion | ISS | biological_process |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | ISS | biological_process |
| GO:0010976 | Positive regulation of neuron projection development | ISS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0042734 | Presynaptic membrane | ISS | cellular_component |
| GO:0045743 | Positive regulation of fibroblast growth factor receptor signaling pathway | ISS | biological_process |
| GO:0048170 | Positive regulation of long-term neuronal synaptic plasticity | ISS | biological_process |
| GO:0050839 | Cell adhesion molecule binding | ISS | molecular_function |
| GO:0060291 | Long-term synaptic potentiation | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5803126667 | 0.5334692869 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1810289871 |
| GSE13712_SHEAR | Down | -0.0190796305 |
| GSE13712_STATIC | Down | -0.1335671271 |
| GSE19018 | Down | -0.0088498620 |
| GSE19899_A1 | Up | 0.0092190951 |
| GSE19899_A2 | Down | -0.0259518887 |
| PubMed_21979375_A1 | Down | -0.1035336335 |
| PubMed_21979375_A2 | Down | -0.1019985439 |
| GSE35957 | Up | 0.1685034113 |
| GSE36640 | Up | 0.4338571401 |
| GSE54402 | Down | -0.1882357220 |
| GSE9593 | Up | 0.3155114514 |
| GSE43922 | Down | -0.0145456563 |
| GSE24585 | Up | 0.2721521799 |
| GSE37065 | Up | 0.1493491092 |
| GSE28863_A1 | Up | 0.4165189837 |
| GSE28863_A2 | Up | 0.0877571519 |
| GSE28863_A3 | Down | -0.1716149567 |
| GSE28863_A4 | Down | -0.0051020974 |
| GSE48662 | Down | -0.2705600553 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023641 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029137 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037907 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046088 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051931 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
